Transcriptional Regulator ERG
"Transcriptional Regulator ERG" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trans-activator and member of the erythroblast transformation-specific family of transcriptions factors that contain a characteristic ETS MOTIF. It is required for PLATELET CELL ADHESION to the subendothelium and associates with CHIMERIC ONCOGENE PROTEINS in PROSTATE CANCER; EWING'S SARCOMA; and ACUTE MYELOID LEUKEMIA.
| Descriptor ID |
D000071230
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| MeSH Number(s) |
D12.776.260.755.100 D12.776.930.900.625
|
| Concept/Terms |
Transcriptional Regulator ERG- Transcriptional Regulator ERG
- Transforming Protein ERG
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Homolog Protein
- V-Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
- V Ets Avian Erythroblastosis Virus E26 Oncogene Related Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcriptional Regulator ERG".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Regulator ERG".
This graph shows the total number of publications written about "Transcriptional Regulator ERG" by people in this website by year, and whether "Transcriptional Regulator ERG" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcriptional Regulator ERG" by people in Profiles.
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Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge. Arterioscler Thromb Vasc Biol. 2023 08; 43(8):1412-1428.
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PGC1 alpha coactivates ERG fusion to drive antioxidant target genes under metabolic stress. Commun Biol. 2022 05 04; 5(1):416.
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An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression. Proc Natl Acad Sci U S A. 2020 10 20; 117(42):26494-26502.
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ETS transcription factor ERG cooperates with histone demethylase KDM4A. Oncol Rep. 2016 Jun; 35(6):3679-88.
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Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6091-6.
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Modulation of HERG potassium channels by extracellular magnesium and quinidine. J Cardiovasc Pharmacol. 1999 Feb; 33(2):181-5.