"Pharmacogenomic Variants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).
| Descriptor ID |
D000071184
|
| MeSH Number(s) |
G05.365.795.446
|
| Concept/Terms |
Pharmacogenomic Variants- Pharmacogenomic Variants
- Pharmacogenomic Variant
- Variant, Pharmacogenomic
- Variants, Pharmacogenomic
- Pharmacokinetic Genetic Variants
- Genetic Variant, Pharmacokinetic
- Genetic Variants, Pharmacokinetic
- Pharmacokinetic Genetic Variant
- Pharmacogenetic Variants
- Pharmacogenetic Variant
- Variant, Pharmacogenetic
- Variants, Pharmacogenetic
|
Below are MeSH descriptors whose meaning is more general than "Pharmacogenomic Variants".
Below are MeSH descriptors whose meaning is more specific than "Pharmacogenomic Variants".
This graph shows the total number of publications written about "Pharmacogenomic Variants" by people in this website by year, and whether "Pharmacogenomic Variants" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pharmacogenomic Variants" by people in Profiles.
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AICM: A Genuine Framework for Correcting Inconsistency Between Large Pharmacogenomics Datasets. Pac Symp Biocomput. 2019; 24:248-259.
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Clinical Evaluation of Cisplatin Sensitivity of Germline Polymorphisms in Neoadjuvant Chemotherapy for Urothelial Cancer. Clin Genitourin Cancer. 2016 12; 14(6):511-517.