Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
| Descriptor ID |
D018807
|
| MeSH Number(s) |
G05.365.795.600
|
| Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
|
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Effects of cryogenic preservation and storage on the molecular characteristics of microorganisms in sediments. Environ Sci Technol. 2010 Nov 01; 44(21):8243-7.
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Polymorphic MHC loci in an asexual fish, the amazon molly (Poecilia formosa; Poeciliidae). Mol Ecol. 2008 Dec; 17(24):5220-30.
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Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assay. Appl Immunohistochem Mol Morphol. 2004 Dec; 12(4):373-9.
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Granulomatous eccrinotropic lymphomatoid papulosis. Am J Clin Pathol. 2003 May; 119(5):731-9.
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Pityriasis lichenoides: a clonal T-cell lymphoproliferative disorder. Hum Pathol. 2002 Aug; 33(8):788-95.
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Novel mutation in the TIMP3 gene causes Sorsby fundus dystrophy. Arch Ophthalmol. 2002 Mar; 120(3):376-9.
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Genetic screening of the lipoprotein lipase gene for mutations associated with high triglyceride/low HDL-cholesterol levels. Hum Genet. 2000 Sep; 107(3):257-67.
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A novel mutation in the apolipoprotein E gene (APOE*4 Pittsburgh) is associated with the risk of late-onset Alzheimer's disease. Neurosci Lett. 1999 Mar 26; 263(2-3):129-32.
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Partial growth-hormone insensitivity: the role of growth-hormone receptor mutations in idiopathic short stature. J Pediatr. 1997 Jul; 131(1 Pt 2):S51-5.
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Familial pheochromocytoma due to mutant von Hippel-Lindau disease gene. Arch Intern Med. 1997 Jun 23; 157(12):1390-1.