"Anisomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
| Descriptor ID |
D000841
|
| MeSH Number(s) |
D03.383.773.050
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Anisomycin".
Below are MeSH descriptors whose meaning is more specific than "Anisomycin".
This graph shows the total number of publications written about "Anisomycin" by people in this website by year, and whether "Anisomycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Anisomycin" by people in Profiles.
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Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J Mol Biol. 2008 Jun 06; 379(3):505-19.
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Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase. J Biol Chem. 2003 Jun 06; 278(23):20593-602.
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Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6606-11.