Antibody Specificity

"Antibody Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.

Descriptor ID	D000918
MeSH Number(s)	G12.100
Concept/Terms	Antibody Specificity Antibody Specificity Antibody Specificities Specificities, Antibody Specificity, Antibody

Below are MeSH descriptors whose meaning is more general than "Antibody Specificity".

Biological Sciences [G]
Immune System Phenomena [G12]
Antibody Specificity [G12.100]

Below are MeSH descriptors whose meaning is more specific than "Antibody Specificity".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antibody Specificity" by people in this website by year, and whether "Antibody Specificity" was a major or minor topic of these publications.

Bar chart showing 74 publications over 28 distinct years, with a maximum of 7 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1993	1	3	4
1994	1	1	2
1995	0	1	1
1996	0	5	5
1997	0	5	5
1998	0	1	1
1999	3	0	3
2000	0	1	1
2001	0	1	1
2002	2	5	7
2003	1	1	2
2004	0	1	1
2005	0	4	4
2006	1	3	4
2007	1	4	5
2008	0	3	3
2009	1	2	3
2010	0	1	1
2011	2	3	5
2012	1	2	3
2013	0	2	2
2014	1	1	2
2015	0	2	2
2016	1	1	2
2017	1	0	1
2020	0	2	2
2021	0	1	1

Below are the most recent publications written about "Antibody Specificity" by people in Profiles.

Bachmann MP, Bartsch T, Bippes CC, Bachmann D, Puentes-Cala E, Bachmann J, Bartsch H, Arndt C, Koristka S, Loureiro LR, Kegler A, Laube M, Gross JK, Gross T, Kurien BT, Scofield RH, Farris AD, James JA, Schmitz M, Feldmann A. T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation. Int J Mol Sci. 2021 Jan 26; 22(3).

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Keating R, Johnson JL, Brice DC, Labombarde JG, Dent AL, McGargill MA. Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies. mBio. 2020 11 03; 11(6).

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Dumas EK, Demiraslan H, Ingram RJ, Sparks RM, Muns E, Zamora A, Larabee J, Garman L, Ballard JD, Boons GJ, James JA, Kayabas U, Doganay M, Farris AD. Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS One. 2020; 15(4):e0230782.

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Kurien BT, Scofield RH. Validating Antibody Specificities for Immunohistochemistry by Protein Blotting Methods. Methods Mol Biol. 2017; 1554:61-73.

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Smith K, Shah H, Muther JJ, Duke AL, Haley K, James JA. Antigen nature and complexity influence human antibody light chain usage and specificity. Vaccine. 2016 05 27; 34(25):2813-20.

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Kaabinejadian S, McMurtrey CP, Kim S, Jain R, Bardet W, Schafer FB, Davenport JL, Martin AD, Diamond MS, Weidanz JA, Hansen TH, Hildebrand WH. Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late. J Immunol. 2016 05 15; 196(10):4263-73.

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Patterson AM, Kaabinejadian S, McMurtrey CP, Bardet W, Jackson KW, Zuna RE, Husain S, Adams GP, MacDonald G, Dillon RL, Ames H, Buchli R, Hawkins OE, Weidanz JA, Hildebrand WH. Human Leukocyte Antigen-Presented Macrophage Migration Inhibitory Factor Is a Surface Biomarker and Potential Therapeutic Target for Ovarian Cancer. Mol Cancer Ther. 2016 Feb; 15(2):313-22.

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Kurien BT, Scofield RH. Analysis of antibody clonotype by affinity immunoblotting. Methods Mol Biol. 2015; 1312:109-17.

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Maier-Moore JS, Koelsch KA, Smith K, Lessard CJ, Radfar L, Lewis D, Kurien BT, Wolska N, Deshmukh U, Rasmussen A, Sivils KL, James JA, Farris AD, Scofield RH. Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome. Arthritis Rheumatol. 2014 Dec; 66(12):3445-56.

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Hanigan MH, Gillies EM, Wickham S, Wakeham N, Wirsig-Wiechmann CR. Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1. Histochem Cell Biol. 2015 May; 143(5):505-15.

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