"Aldehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
| Descriptor ID |
D000444
|
| MeSH Number(s) |
D08.811.682.657.163.249
|
| Concept/Terms |
Aldehyde Dehydrogenase- Aldehyde Dehydrogenase
- Dehydrogenase, Aldehyde
- D-Glucuronolactone Dehydrogenase
- D Glucuronolactone Dehydrogenase
- Dehydrogenase, D-Glucuronolactone
- Aldehyde Dehydrogenase (NAD(+))
- Aldehyde-NAD Oxidoreductase
- Aldehyde NAD Oxidoreductase
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Dehydrogenase".
This graph shows the total number of publications written about "Aldehyde Dehydrogenase" by people in this website by year, and whether "Aldehyde Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Dehydrogenase" by people in Profiles.
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3D-QSAR and scaffold hopping based designing of benzo[d]ox-azol-2(3H)-one and 2-oxazolo[4,5-b]pyridin-2(3H)-one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation. Arch Pharm (Weinheim). 2022 Sep; 355(9):e2200108.
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Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem. 2018 12 01; 26(22):5766-5779.
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Disulfiram's Anticancer Activity: Evidence and Mechanisms. Anticancer Agents Med Chem. 2016; 16(11):1378-1384.
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ß-Escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells. Cancer Prev Res (Phila). 2013 Oct; 6(10):1140-9.
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MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell. 2009 Jan 06; 15(1):9-20.