"Aldehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
| Descriptor ID |
D000444
|
| MeSH Number(s) |
D08.811.682.657.163.249
|
| Concept/Terms |
Aldehyde Dehydrogenase- Aldehyde Dehydrogenase
- Dehydrogenase, Aldehyde
- D-Glucuronolactone Dehydrogenase
- D Glucuronolactone Dehydrogenase
- Dehydrogenase, D-Glucuronolactone
- Aldehyde Dehydrogenase (NAD(+))
- Aldehyde-NAD Oxidoreductase
- Aldehyde NAD Oxidoreductase
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Dehydrogenase".
This graph shows the total number of publications written about "Aldehyde Dehydrogenase" by people in this website by year, and whether "Aldehyde Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Dehydrogenase" by people in Profiles.
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Disruption of aldehyde dehydrogenase decreases cell wall-bound p-hydroxycinnamates and improves cell wall digestibility in rice. Plant J. 2024 Dec; 120(6):2828-2845.
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Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem. 2018 12 01; 26(22):5766-5779.
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Disulfiram's Anticancer Activity: Evidence and Mechanisms. Anticancer Agents Med Chem. 2016; 16(11):1378-1384.
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ß-Escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells. Cancer Prev Res (Phila). 2013 Oct; 6(10):1140-9.
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Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos. 2010 Oct; 38(10):1679-87.
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MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell. 2009 Jan 06; 15(1):9-20.
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Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene. Mol Ther. 2001 Jan; 3(1):88-96.