"Calcium Channel Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
| Descriptor ID |
D002120
|
| MeSH Number(s) |
D27.505.519.562.124 D27.505.954.411.793.205
|
| Concept/Terms |
Calcium Channel Agonists- Calcium Channel Agonists
- Agonists, Calcium Channel
- Channel Agonists, Calcium
- Calcium Channel Activators
- Activators, Calcium Channel
- Channel Activators, Calcium
- Calcium Channel Agonist
- Agonist, Calcium Channel
- Channel Agonist, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Channel Agonists".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channel Agonists".
This graph shows the total number of publications written about "Calcium Channel Agonists" by people in this website by year, and whether "Calcium Channel Agonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calcium Channel Agonists" by people in Profiles.
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Turtle Flexion Reflex Motor Patterns Show Windup, Mediated Partly by L-type Calcium Channels. Front Neural Circuits. 2017; 11:83.
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Serotonin reuptake inhibitor fluoxetine decreases arteriolar myogenic tone by reducing smooth muscle [Ca2+]i. J Cardiovasc Pharmacol. 2000 Jun; 35(6):849-54.
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Increased myogenic tone in skeletal muscle arterioles of diabetic rats. Possible role of increased activity of smooth muscle Ca2+ channels and protein kinase C. Cardiovasc Res. 1999 Sep; 43(4):1018-28.
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Fluoxetine dilates isolated small cerebral arteries of rats and attenuates constrictions to serotonin, norepinephrine, and a voltage-dependent Ca(2+) channel opener. Stroke. 1999 Sep; 30(9):1949-54.
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Ovariectomy and estrogen-induced alterations in myocardial contractility in female rabbits: role of the L-type calcium channel. J Pharmacol Exp Ther. 1998 Feb; 284(2):586-91.
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Effect of 17-beta estradiol in the rabbit: endothelium-dependent and -independent mechanisms of vascular relaxation. J Cardiovasc Pharmacol. 1997 Jul; 30(1):130-5.
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Early afterdepolarizations produced by d,l-sotalol and clofilium. J Cardiovasc Electrophysiol. 1997 Jun; 8(6):667-78.