"Ionophores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
| Descriptor ID |
D007476
|
| MeSH Number(s) |
D27.505.519.562.374 D27.720.395
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ionophores".
Below are MeSH descriptors whose meaning is more specific than "Ionophores".
This graph shows the total number of publications written about "Ionophores" by people in this website by year, and whether "Ionophores" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ionophores" by people in Profiles.
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Metal ionophores - an emerging class of anticancer drugs. IUBMB Life. 2009 Nov; 61(11):1013-8.
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Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem. 2007 Apr 20; 282(16):11629-38.
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Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol Cancer Ther. 2006 Jul; 5(7):1864-72.
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Growth of bone marrow stromal cells on small intestinal submucosa: an alternative cell source for tissue engineered bladder. BJU Int. 2005 Nov; 96(7):1120-5.
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Intracellular calcium transients are necessary for platelet-derived growth factor but not extracellular matrix protein-induced vascular smooth muscle cell migration. J Vasc Surg. 2004 Aug; 40(2):351-8.
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Role of endothelial [Ca2+]i in activation of eNOS in pressurized arterioles by agonists and wall shear stress. Am J Physiol Heart Circ Physiol. 2001 Aug; 281(2):H606-12.
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Characterization of cultured bladder smooth muscle cells: assessment of in vitro contractility. J Urol. 1999 Nov; 162(5):1779-84.
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Different pH dependency of mitomycin C activity in monolayer and three-dimensional cultures. Pharm Res. 1996 Dec; 13(12):1887-91.