Cyclic AMP

"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.

Descriptor ID	D000242
MeSH Number(s)	D03.633.100.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
Concept/Terms	Cyclic AMP Cyclic AMP AMP, Cyclic Adenosine Cyclic-3',5'-Monophosphate Cyclic-3',5'-Monophosphate, Adenosine Adenosine Cyclic Monophosphate Cyclic Monophosphate, Adenosine Monophosphate, Adenosine Cyclic Adenosine Cyclic 3,5 Monophosphate Adenosine Cyclic 3',5'-Monophosphate 3',5'-Monophosphate, Adenosine Cyclic Adenosine Cyclic 3',5' Monophosphate Cyclic 3',5'-Monophosphate, Adenosine Cyclic AMP, Monosodium Salt Cyclic AMP, Monosodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Sodium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, Monoammonium Salt Cyclic AMP, (R)-Isomer Cyclic AMP, (R)-Isomer Cyclic AMP, Disodium Salt Cyclic AMP, Disodium Salt Cyclic AMP, Monopotassium Salt Cyclic AMP, Monopotassium Salt

Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Adenine Nucleotides [D03.633.100.759.646.138]
Cyclic AMP [D03.633.100.759.646.138.395]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Nucleotides, Cyclic [D13.695.462]
Cyclic AMP [D13.695.462.200]
Purine Nucleotides [D13.695.667]
Adenine Nucleotides [D13.695.667.138]
Cyclic AMP [D13.695.667.138.395]
Ribonucleotides [D13.695.827]
Adenine Nucleotides [D13.695.827.068]
Cyclic AMP [D13.695.827.068.395]

Below are MeSH descriptors whose meaning is related to "Cyclic AMP".

Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.

Bar chart showing 47 publications over 25 distinct years, with a maximum of 4 publications in 1996 and 2003 and 2008 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	1	1
1992	2	1	3
1993	0	2	2
1994	0	1	1
1995	0	1	1
1996	0	4	4
1998	0	1	1
1999	0	1	1
2000	0	1	1
2001	0	1	1
2002	0	3	3
2003	1	3	4
2005	1	0	1
2007	1	2	3
2008	0	4	4
2009	0	1	1
2010	0	2	2
2011	1	3	4
2012	1	1	2
2013	1	1	2
2014	0	1	1
2016	1	0	1
2018	0	1	1
2019	0	1	1
2020	0	1	1

Below are the most recent publications written about "Cyclic AMP" by people in Profiles.

Roehrkasse AM, Warner ML, Booe JM, Pioszak AA. Biochemical characterization of G protein coupling to calcitonin gene-related peptide and adrenomedullin receptors using a native PAGE assay. J Biol Chem. 2020 07 10; 295(28):9736-9751.

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Pan Z, Dumas EK, Lawrence C, Pate L, Longobardi S, Wang X, James JA, Kovats S, Farris AD. Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling. Int J Mol Sci. 2019 Mar 07; 20(5).

View in: PubMed
Larabee JL, Hauck G, Ballard JD. Unique, Intersecting, and Overlapping Roles of C/EBP ß and CREB in Cells of the Innate Immune System. Sci Rep. 2018 11 16; 8(1):16931.

View in: PubMed
Blackwood BP, Wood DR, Yuan C, Nicolas J, De Plaen IG, Farrow KN, Chou P, Turner JR, Hunter CJ. A Role for cAMP and Protein Kinase A in Experimental Necrotizing Enterocolitis. Am J Pathol. 2017 Feb; 187(2):401-417.

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Singh N, Yadav M, Singh AK, Kumar H, Dwivedi SK, Mishra JS, Gurjar A, Manhas A, Chandra S, Yadav PN, Jagavelu K, Siddiqi MI, Trivedi AK, Chattopadhyay N, Sanyal S. Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptors. Mol Endocrinol. 2014 May; 28(5):659-73.

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Ha JH, Ward JD, Varadarajalu L, Kim SG, Dhanasekaran DN. The gep proto-oncogene Ga12 mediates LPA-stimulated activation of CREB in ovarian cancer cells. Cell Signal. 2014 Jan; 26(1):122-32.

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Larabee JL, Shakir SM, Barua S, Ballard JD. Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem. 2013 Jul 26; 288(30):21526-36.

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Weems JC, Griesel BA, Olson AL. Class II histone deacetylases downregulate GLUT4 transcription in response to increased cAMP signaling in cultured adipocytes and fasting mice. Diabetes. 2012 Jun; 61(6):1404-14.

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Franko-Tobin LG, Mackey LV, Huang W, Song X, Jin B, Luo J, Morris LM, Liu M, Fuselier JA, Coy DH, Wu L, Sun L. Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics. Oncologist. 2012; 17(2):220-32.

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Chen A, Dong L, Leffler NR, Asch AS, Witte ON, Yang LV. Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway. PLoS One. 2011; 6(11):e27586.

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