"Cell Nucleolus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA, RIBOSOMAL) are synthesized and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rRNA is transcribed from a nucleolar organizer, i.e., a group of tandemly repeated chromosomal genes which encode rRNA and which are transcribed by RNA polymerase I. (Singleton & Sainsbury, Dictionary of Microbiology & Molecular Biology, 2d ed)
Descriptor ID |
D002466
|
MeSH Number(s) |
A11.284.430.106.279.345.175
|
Concept/Terms |
Cell Nucleolus- Cell Nucleolus
- Plasmosome
- Plasmosomes
- Cell Nucleoli
- Nucleoli, Cell
- Nucleolus, Cell
|
Below are MeSH descriptors whose meaning is more general than "Cell Nucleolus".
Below are MeSH descriptors whose meaning is more specific than "Cell Nucleolus".
This graph shows the total number of publications written about "Cell Nucleolus" by people in this website by year, and whether "Cell Nucleolus" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 1 | 2 |
2000 | 1 | 1 | 2 |
2001 | 0 | 1 | 1 |
2002 | 1 | 3 | 4 |
2003 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Nucleolus" by people in Profiles.
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McNamar R, Rothblum K, Rothblum LI. The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same. Genes (Basel). 2021 04 22; 12(5).
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Stepanchick A, Zhi H, Cavanaugh AH, Rothblum K, Schneider DA, Rothblum LI. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription. J Biol Chem. 2013 Mar 29; 288(13):9135-44.
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Kamieniecki RJ, Liu L, Dawson DS. FEAR but not MEN genes are required for exit from meiosis I. Cell Cycle. 2005 Aug; 4(8):1093-8.
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Sansam CL, Wells KS, Emeson RB. Modulation of RNA editing by functional nucleolar sequestration of ADAR2. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14018-23.
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Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T. A kinetic framework for a mammalian RNA polymerase in vivo. Science. 2002 Nov 22; 298(5598):1623-6.
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Sawalha AH, Namjou B, Nath SK, Kilpatrick J, Germundson A, Kelly JA, Hutchings D, James J, Harley J. Genetic linkage of systemic lupus erythematosus with chromosome 11q14 (SLEH1) in African-American families stratified by a nucleolar antinuclear antibody pattern. Genes Immun. 2002 Oct; 3 Suppl 1:S31-4.
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De Haro L, Janknecht R. Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter. Nucleic Acids Res. 2002 Jul 01; 30(13):2972-9.
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Cavanaugh AH, Hirschler-Laszkiewicz I, Hu Q, Dundr M, Smink T, Misteli T, Rothblum LI. Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem. 2002 Jul 26; 277(30):27423-32.
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Hirschler-Laszkiewicz I, Cavanaugh A, Hu Q, Catania J, Avantaggiati ML, Rothblum LI. The role of acetylation in rDNA transcription. Nucleic Acids Res. 2001 Oct 15; 29(20):4114-24.
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Hannan KM, Kennedy BK, Cavanaugh AH, Hannan RD, Hirschler-Laszkiewicz I, Jefferson LS, Rothblum LI. RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest. Oncogene. 2000 Jul 20; 19(31):3487-97.