Fibrinogen

"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

Descriptor ID	D005340
MeSH Number(s)	D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
Concept/Terms	Fibrinogen Fibrinogen Blood Coagulation Factor I Coagulation Factor I Factor I, Coagulation Factor I gamma-Fibrinogen gamma-Fibrinogen gamma Fibrinogen

Below are MeSH descriptors whose meaning is more general than "Fibrinogen".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Acute-Phase Proteins [D12.776.124.050]
Fibrinogen [D12.776.124.050.250]
Blood Coagulation Factors [D12.776.124.125]
Fibrinogen [D12.776.124.125.500]
Protein Precursors [D12.776.811]
Fibrinogen [D12.776.811.300]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Fibrinogen [D23.119.490]

Below are MeSH descriptors whose meaning is related to "Fibrinogen".

Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".

Fibrinogen
Fibrinogens, Abnormal

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.

Bar chart showing 28 publications over 16 distinct years, with a maximum of 4 publications in 1991 and 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	0	4	4
1994	1	0	1
1996	2	2	4
2000	0	2	2
2001	0	1	1
2003	0	1	1
2004	1	1	2
2006	0	1	1
2008	2	0	2
2009	0	1	1
2011	0	1	1
2012	0	1	1
2014	0	1	1
2015	1	1	2
2017	0	1	1
2020	1	2	3

Below are the most recent publications written about "Fibrinogen" by people in Profiles.

Sung AD, Yen RC, Jiao Y, Bernanke A, Lewis DA, Miller SE, Li Z, Ross JR, Artica A, Piryani S, Zhou D, Liu Y, Vo-Dinh T, Hoffman M, Ortel TL, Chao NJ, Chen BJ. Fibrinogen-Coated Albumin Nanospheres Prevent Thrombocytopenia-Related Bleeding. Radiat Res. 2020 08 01; 194(2):162-172.

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Merrill JT, Erkan D, Winakur J, James JA. Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications. Nat Rev Rheumatol. 2020 10; 16(10):581-589.

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Guo X, Eitnier RA, Beard RS, Meegan JE, Yang X, Aponte AM, Wang F, Nelson PR, Wu MH. Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- ?C- terminal fragments. PLoS One. 2020; 15(4):e0231739.

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Williams KL, Woslager M, Garland SL, Barton RP, Banner W. Use of polyvalent equine anti-viper serum to treat delayed coagulopathy due to suspected Sistrurus miliarius streckeri envenomation in two children. Clin Toxicol (Phila). 2017 Jun; 55(5):326-331.

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Ma L, Cheng C, He C, Nie C, Deng J, Sun S, Zhao C. Substrate-Independent Robust and Heparin-Mimetic Hydrogel Thin Film Coating via Combined LbL Self-Assembly and Mussel-Inspired Post-Cross-linking. ACS Appl Mater Interfaces. 2015 Dec 02; 7(47):26050-62.

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Zhang G, Niu G, Franca CM, Dong Y, Wang X, Butler NS, Dimopoulos G, Li J. Anopheles Midgut FREP1 Mediates Plasmodium Invasion. J Biol Chem. 2015 Jul 03; 290(27):16490-501.

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Maiti AK, Kim-Howard X, Motghare P, Pradhan V, Chua KH, Sun C, Arango-Guerrero MT, Ghosh K, Niewold TB, Harley JB, Anaya JM, Looger LL, Nath SK. Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM. Hum Mol Genet. 2014 Aug 01; 23(15):4161-76.

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Capaldo B, Di Bonito P, Iaccarino M, Roman MJ, Lee ET, Devereux RB, Riccardi G, Howard BV, de Simone G. Cardiovascular characteristics in subjects with increasing levels of abnormal glucose regulation: the Strong Heart Study. Diabetes Care. 2013 Apr; 36(4):992-7.

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Karas MG, Devereux RB, Wiebers DO, Whisnant JP, Best LG, Lee ET, Howard BV, Roman MJ, Umans JG, Kizer JR. Incremental value of biochemical and echocardiographic measures in prediction of ischemic stroke: the Strong Heart Study. Stroke. 2012 Mar; 43(3):720-6.

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Taylor ZR, Patel K, Spain TG, Keay JC, Jernigen JD, Sanchez ES, Grady BP, Johnson MB, Schmidtke DW. Fabrication of protein dot arrays via particle lithography. Langmuir. 2009 Sep 15; 25(18):10932-8.

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