Fibrinogen

"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

Descriptor ID	D005340
MeSH Number(s)	D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
Concept/Terms	Fibrinogen Fibrinogen Blood Coagulation Factor I Coagulation Factor I Factor I, Coagulation Factor I gamma-Fibrinogen gamma-Fibrinogen gamma Fibrinogen

Below are MeSH descriptors whose meaning is more general than "Fibrinogen".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Acute-Phase Proteins [D12.776.124.050]
Fibrinogen [D12.776.124.050.250]
Blood Coagulation Factors [D12.776.124.125]
Fibrinogen [D12.776.124.125.500]
Protein Precursors [D12.776.811]
Fibrinogen [D12.776.811.300]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Fibrinogen [D23.119.490]

Below are MeSH descriptors whose meaning is related to "Fibrinogen".

Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".

Fibrinogen
Fibrinogens, Abnormal

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.

Bar chart showing 23 publications over 15 distinct years, with a maximum of 4 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1996	2	2	4
2000	0	2	2
2001	0	1	1
2003	0	1	1
2004	1	1	2
2006	0	1	1
2008	2	0	2
2009	0	1	1
2011	0	1	1
2012	0	1	1
2014	0	1	1
2015	1	0	1
2017	0	1	1
2020	1	2	3

Below are the most recent publications written about "Fibrinogen" by people in Profiles.

Coales EM, Ajjan RA, Pearson SM, O'Mahoney LL, Kietsiriroje N, Brož J, Holmes M, Campbell MD. Application of Machine Learning to Assess Interindividual Variability in Rapid-Acting Insulin Responses After Subcutaneous Injection in People With Type 1 Diabetes. Can J Diabetes. 2022 Apr; 46(3):225-232.e2.

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O'Mahoney LL, Kietsiriroje N, Pearson S, West DJ, Holmes M, Ajjan RA, Campbell MD. Estimated glucose disposal rate as a candidate biomarker for thrombotic biomarkers in T1D: a pooled analysis. J Endocrinol Invest. 2021 Nov; 44(11):2417-2426.

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Sung AD, Yen RC, Jiao Y, Bernanke A, Lewis DA, Miller SE, Li Z, Ross JR, Artica A, Piryani S, Zhou D, Liu Y, Vo-Dinh T, Hoffman M, Ortel TL, Chao NJ, Chen BJ. Fibrinogen-Coated Albumin Nanospheres Prevent Thrombocytopenia-Related Bleeding. Radiat Res. 2020 08 01; 194(2):162-172.

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Merrill JT, Erkan D, Winakur J, James JA. Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications. Nat Rev Rheumatol. 2020 10; 16(10):581-589.

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Guo X, Eitnier RA, Beard RS, Meegan JE, Yang X, Aponte AM, Wang F, Nelson PR, Wu MH. Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- ?C- terminal fragments. PLoS One. 2020; 15(4):e0231739.

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Bolliger D, Tanaka KA. More Is Not Always Better: Effects of Cell Salvage in Cardiac Surgery on Postoperative Fibrinogen Concentrations. J Cardiothorac Vasc Anesth. 2020 09; 34(9):2383-2385.

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Chow JH, Richards JE, Morrison JJ, Galvagno SM, Tanaka KA, Madurska MJ, Rock P, Scalea TM, Mazzeffi MA. Viscoelastic Signals for Optimal Resuscitation in Trauma: Kaolin Thrombelastography Cutoffs for Diagnosing Hypofibrinogenemia (VISOR Study). Anesth Analg. 2019 12; 129(6):1482-1491.

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Henderson RA, Mazzeffi MA, Tanaka KA. Fibrinogen Concentrate: Is It Standard Currency or Bitcoin in Bleeding Management? Anesth Analg. 2018 09; 127(3):603-604.

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Chow JH, Lee K, Abuelkasem E, Udekwu OR, Tanaka KA. Coagulation Management During Liver Transplantation: Use of Fibrinogen Concentrate, Recombinant Activated Factor VII, Prothrombin Complex Concentrate, and Antifibrinolytics. Semin Cardiothorac Vasc Anesth. 2018 Jun; 22(2):164-173.

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Williams KL, Woslager M, Garland SL, Barton RP, Banner W. Use of polyvalent equine anti-viper serum to treat delayed coagulopathy due to suspected Sistrurus miliarius streckeri envenomation in two children. Clin Toxicol (Phila). 2017 Jun; 55(5):326-331.

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