"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
| Descriptor ID |
D008024
|
| MeSH Number(s) |
D27.720.470.480
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1999 | 0 | 6 | 6 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 8 | 8 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 6 | 6 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 3 | 3 |
| 2007 | 1 | 7 | 8 |
| 2008 | 0 | 9 | 9 |
| 2009 | 0 | 5 | 5 |
| 2010 | 0 | 9 | 9 |
| 2011 | 0 | 7 | 7 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 5 | 5 |
| 2014 | 1 | 7 | 8 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 7 | 7 |
| 2017 | 0 | 5 | 5 |
| 2018 | 0 | 6 | 6 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 7 | 7 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 3 | 3 |
| 2024 | 0 | 3 | 3 |
| 2025 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Ligands" by people in Profiles.
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Cardiotropic ligand-guided liposomes for myocardial delivery of atorvastatin in a mouse model of myocardial infarction. Int J Pharm. 2025 Aug 20; 681:125841.
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CACHE Challenge #1: Docking with GNINA Is All You Need. J Chem Inf Model. 2024 Dec 23; 64(24):9388-9396.
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CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein. J Chem Inf Model. 2024 Nov 25; 64(22):8521-8536.
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Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation. Commun Biol. 2024 Feb 24; 7(1):228.
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FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer. Breast Cancer Res. 2023 08 22; 25(1):99.
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Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4. J Med Chem. 2023 03 23; 66(6):3866-3875.
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Decursin inhibits EGFR-ERK1/2 signaling axis in advanced human prostate carcinoma cells. Prostate. 2023 May; 83(6):534-546.
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Molecular basis for coordinating secondary metabolite production by bacterial and plant signaling molecules. J Biol Chem. 2022 06; 298(6):102027.
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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome. Front Immunol. 2022; 13:835454.
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Use of a Clostridioides difficile Murine Immunization and Challenge Model to Evaluate Single and Combination Vaccine Adjuvants Consisting of Alum and NKT Cell-Activating Ligands. Front Immunol. 2021; 12:818734.