Gonadotropin-Releasing Hormone

"Gonadotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.

Descriptor ID	D007987
MeSH Number(s)	D06.472.699.327.740.320 D12.644.400.400.740.320 D12.644.456.460 D12.644.548.365.740.320 D12.776.631.650.405.740.320
Concept/Terms	Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gonadotropin Releasing Hormone Gn-RH Gonadoliberin LHFSH Releasing Hormone Releasing Hormone, LHFSH LH-RH LFRH LH-Releasing Hormone LH Releasing Hormone LH-FSH Releasing Hormone LH FSH Releasing Hormone LHFSHRH LHRH Luliberin Gonadorelin Luteinizing Hormone-Releasing Hormone Luteinizing Hormone Releasing Hormone FSH-Releasing Hormone FSH Releasing Hormone GnRH Factrel Factrel Cystorelin Cystorelin Gonadorelin Hydrochloride Gonadorelin Hydrochloride Kryptocur Kryptocur Dirigestran Dirigestran Gonadorelin Acetate Gonadorelin Acetate

Below are MeSH descriptors whose meaning is more general than "Gonadotropin-Releasing Hormone".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Hypothalamic Hormones [D06.472.699.327]
Pituitary Hormone-Releasing Hormones [D06.472.699.327.740]
Gonadotropin-Releasing Hormone [D06.472.699.327.740.320]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Hypothalamic Hormones [D12.644.400.400]
Pituitary Hormone-Releasing Hormones [D12.644.400.400.740]
Gonadotropin-Releasing Hormone [D12.644.400.400.740.320]
Oligopeptides [D12.644.456]
Gonadotropin-Releasing Hormone [D12.644.456.460]
Peptide Hormones [D12.644.548]
Hypothalamic Hormones [D12.644.548.365]
Pituitary Hormone-Releasing Hormones [D12.644.548.365.740]
Gonadotropin-Releasing Hormone [D12.644.548.365.740.320]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Hypothalamic Hormones [D12.776.631.650.405]
Pituitary Hormone-Releasing Hormones [D12.776.631.650.405.740]
Gonadotropin-Releasing Hormone [D12.776.631.650.405.740.320]

Below are MeSH descriptors whose meaning is more specific than "Gonadotropin-Releasing Hormone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gonadotropin-Releasing Hormone" by people in this website by year, and whether "Gonadotropin-Releasing Hormone" was a major or minor topic of these publications.

Bar chart showing 27 publications over 15 distinct years, with a maximum of 5 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	1	1	2
1994	0	1	1
1996	1	0	1
1998	2	0	2
1999	2	0	2
2000	2	0	2
2001	2	1	3
2002	3	2	5
2003	0	1	1
2008	0	1	1
2011	1	0	1
2014	1	0	1
2015	0	2	2
2018	1	0	1
2020	2	0	2

Below are the most recent publications written about "Gonadotropin-Releasing Hormone" by people in Profiles.

Li H, Guo Y, Zhang G, Deng J, Fischer H, Craig LB, Yu X, Kem DC. Gonadotrophin-releasing hormone receptor autoantibodies induce polycystic ovary syndrome-like features in a rat model. Exp Physiol. 2021 04; 106(4):902-912.

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Shore ND, Saad F, Cookson MS, George DJ, Saltzstein DR, Tutrone R, Akaza H, Bossi A, van Veenhuyzen DF, Selby B, Fan X, Kang V, Walling J, Tombal B. Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer. N Engl J Med. 2020 06 04; 382(23):2187-2196.

View in: PubMed
Delaney A, Volochayev R, Meader B, Lee J, Almpani K, Noukelak GY, Henkind J, Chalmers L, Law JR, Williamson KA, Jacobsen CM, Buitrago TP, Perez O, Cho CH, Kaindl A, Rauch A, Steindl K, Garcia JE, Russell BE, Prasad R, Mondal UK, Reigstad HM, Clements S, Kim S, Inoue K, Arora G, Salnikov KB, DiOrio NP, Prada R, Capri Y, Morioka K, Mizota M, Zechi-Ceide RM, Kokitsu-Nakata NM, Tonello C, Vendramini-Pittoli S, da Silva Dalben G, Balasubramanian R, Dwyer AA, Seminara SB, Crowley WF, Plummer L, Hall JE, Graham JM, Lin AE, Shaw ND. Insight Into the Ontogeny of GnRH Neurons From Patients Born Without a Nose. J Clin Endocrinol Metab. 2020 05 01; 105(5).

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Liu Y, Bai JH, Xu XL, Chen ZL, Spicer LJ, Feng T. Effects of N-carbamylglutamate and L-arginine on gonadotrophin-releasing hormone (GnRH) gene expression and secretion in GT1-7 cells. Reprod Fertil Dev. 2018 May; 30(5):759-765.

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Chandra V, Kim JJ, Benbrook DM, Dwivedi A, Rai R. Therapeutic options for management of endometrial hyperplasia. J Gynecol Oncol. 2016 Jan; 27(1):e8.

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Quaas AM, Weedin EA, Hansen KR. On-label and off-label drug use in the treatment of endometriosis. Fertil Steril. 2015 Mar; 103(3):612-25.

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Janakiram NB, Mohammed A, Brewer M, Bryant T, Biddick L, Lightfoot S, Pathuri G, Gali H, Rao CV. Raloxifene and antiestrogenic gonadorelin inhibits intestinal tumorigenesis by modulating immune cells and decreasing stem-like cells. Cancer Prev Res (Phila). 2014 Mar; 7(3):300-9.

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Shore N, Cookson MS, Gittelman MC. Long-term efficacy and tolerability of once-yearly histrelin acetate subcutaneous implant in patients with advanced prostate cancer. BJU Int. 2012 Jan; 109(2):226-32.

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Cohen P, Rogol AD, Deal CL, Saenger P, Reiter EO, Ross JL, Chernausek SD, Savage MO, Wit JM. Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. J Clin Endocrinol Metab. 2008 Nov; 93(11):4210-7.

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Hansen KR, Morris JL, Thyer AC, Soules MR. Reproductive aging and variability in the ovarian antral follicle count: application in the clinical setting. Fertil Steril. 2003 Sep; 80(3):577-83.

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