Interleukin-2

"Interleukin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.

Descriptor ID	D007376
MeSH Number(s)	D12.644.276.374.465.021 D12.644.276.374.480.372 D12.776.467.374.465.021 D12.776.467.374.480.372 D23.529.374.465.155 D23.529.374.480.372
Concept/Terms	Interleukin-2 Interleukin-2 Interleukin 2 IL-2 IL2 TCGF Interleukine 2 Lymphocyte Mitogenic Factor Mitogenic Factor, Lymphocyte T-Cell Growth Factor T Cell Growth Factor T-Cell Stimulating Factor T Cell Stimulating Factor Thymocyte Stimulating Factor Interleukin II Ro-23-6019 Ro-23-6019 Ro 23 6019 Ro236019 Ro-236019 Ro 236019 RU 49637 RU 49637 RU-49637 RU49637

Below are MeSH descriptors whose meaning is more general than "Interleukin-2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-2 [D12.644.276.374.465.021]
Lymphokines [D12.644.276.374.480]
Interleukin-2 [D12.644.276.374.480.372]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-2 [D12.776.467.374.465.021]
Lymphokines [D12.776.467.374.480]
Interleukin-2 [D12.776.467.374.480.372]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-2 [D23.529.374.465.155]
Lymphokines [D23.529.374.480]
Interleukin-2 [D23.529.374.480.372]

Below are MeSH descriptors whose meaning is more specific than "Interleukin-2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-2" by people in this website by year, and whether "Interleukin-2" was a major or minor topic of these publications.

Bar chart showing 28 publications over 19 distinct years, with a maximum of 3 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	1	1	2
1992	0	2	2
1994	0	1	1
1995	0	1	1
1996	1	1	2
1997	1	1	2
2003	1	1	2
2004	0	1	1
2005	1	0	1
2006	0	1	1
2007	0	2	2
2009	0	1	1
2010	1	1	2
2011	2	1	3
2012	0	1	1
2013	0	1	1
2017	1	0	1
2018	1	0	1
2020	0	1	1

Below are the most recent publications written about "Interleukin-2" by people in Profiles.

Smith C, Moraka NO, Ibrahim M, Moyo S, Mayondi G, Kammerer B, Leidner J, Gaseitsiwe S, Li S, Shapiro R, Lockman S, Weinberg A. Human Immunodeficiency Virus Exposure but Not Early Cytomegalovirus Infection Is Associated With Increased Hospitalization and Decreased Memory T-Cell Responses to Tetanus Vaccine. J Infect Dis. 2020 03 16; 221(7):1167-1175.

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Tucker P, Pfefferbaum B, Zhao YD, Johnston SE, Mistry A, Khan QS. Associations of biological stress markers in hurricane survivors: Heartrate variability, Interleukin-2 and Interleukin-6 in depression and PTSD. Am J Disaster Med. 2018 Fall; 13(4):267-278.

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Tucker P, Pfefferbaum B, Nitiéma P, Khan Q, Aggarwal R, Walling EE. Possible link of Interleukin-6 and Interleukin-2 with psychiatric diagnosis, ethnicity, disaster or BMI. Cytokine. 2017 08; 96:247-252.

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Koelsch KA, Wang Y, Maier-Moore JS, Sawalha AH, Wren JD. GFP affects human T cell activation and cytokine production following in vitro stimulation. PLoS One. 2013; 8(4):e50068.

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Hagen JW, Magro CM, Crowson AN. Emerging adverse cutaneous drug reactions. Dermatol Clin. 2012 Oct; 30(4):695-730, vii.

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Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Bae SC, Lee JH, Lee JS, Chang DM, Song YW, Yu CY, Kimberly RP, Edberg JC, Brown EE, Petri MA, Ramsey-Goldman R, Vilá LM, Reveille JD, Alarcón-Riquelme ME, Harley JB, Boackle SA, Stevens AM, Scofield RH, Merrill JT, Freedman BI, Anaya JM, Criswell LA, Jacob CO, Vyse TJ, Niewold TB, Gaffney PM, Moser KL, Gilkeson GS, Kamen DL, James JA, Grossman JM, Hahn BH, Tsokos GC, Tsao BP, Alarcón GS. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis Rheum. 2011 Sep; 63(9):2755-63.

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Hughes T, Kim-Howard X, Kelly JA, Kaufman KM, Langefeld CD, Ziegler J, Sanchez E, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Martín J, Brown EE, Vilá LM, Alarcón GS, James JA, Gilkeson GS, Moser KL, Gaffney PM, Merrill JT, Vyse TJ, Alarcón-Riquelme ME, Nath SK, Harley JB, Sawalha AH. Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21. Arthritis Rheum. 2011 Jun; 63(6):1689-97.

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Cox MA, Harrington LE, Zajac AJ. Cytokines and the inception of CD8 T cell responses. Trends Immunol. 2011 Apr; 32(4):180-6.

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Wang S, Zhang M, Liang B, Xu J, Xie Z, Liu C, Viollet B, Yan D, Zou MH. AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes. Circ Res. 2010 Apr 02; 106(6):1117-28.

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Maiti AK, Kim-Howard X, Viswanathan P, Guillén L, Rojas-Villarraga A, Deshmukh H, Direskeneli H, Saruhan-Direskeneli G, Cañas C, Tobön GJ, Sawalha AH, Cherñavsky AC, Anaya JM, Nath SK. Confirmation of an association between rs6822844 at the Il2-Il21 region and multiple autoimmune diseases: evidence of a general susceptibility locus. Arthritis Rheum. 2010 Feb; 62(2):323-9.

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