"Nitrosourea Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds in which the core molecule is R-NO, where R is UREA.
| Descriptor ID |
D009607
|
| MeSH Number(s) |
D02.654.692 D02.948.594
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nitrosourea Compounds".
Below are MeSH descriptors whose meaning is more specific than "Nitrosourea Compounds".
This graph shows the total number of publications written about "Nitrosourea Compounds" by people in this website by year, and whether "Nitrosourea Compounds" was a major or minor topic of these publications.
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Below are the most recent publications written about "Nitrosourea Compounds" by people in Profiles.
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Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. J Clin Oncol. 2002 May 01; 20(9):2277-83.
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Increased cytotoxicity of 1-(2-chloroethyl)-1-nitroso-3(4-methyl)-cyclohexylurea by pretreatment with O6-methylguanine in resistant but not in sensitive human melanoma cells. J Cancer Res Clin Oncol. 1987; 113(4):387-91.
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Ethylation of nucleophilic sites in DNA by N-ethyl-N-nitrosourea depends on chromatin structure and ionic strength. Mutat Res. 1985 Jun-Jul; 150(1-2):13-21.
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Differential formation of O6-ethylguanine in the DNA of rat brain chromatin fibers of different folding levels exposed to N-ethyl-N-nitrosourea in vitro. Cancer Res. 1985 Mar; 45(3):1378-83.
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Highly sensitive sites for guanine-O6 ethylation in rat brain DNA exposed to N-ethyl-N-nitrosourea in vivo. EMBO J. 1984 Feb; 3(2):327-32.
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Comparison of the effect of butylated hydroxytoluene on N-nitrosomethylurea and 7,12-dimethylbenz[a]-anthracene-induced mammary tumors. Cancer Lett. 1981 Dec; 14(3):219-26.