Phosphodiesterase Inhibitors
"Phosphodiesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
| Descriptor ID |
D010726
|
| MeSH Number(s) |
D27.505.519.389.735
|
| Concept/Terms |
Phosphodiesterase Inhibitors- Phosphodiesterase Inhibitors
- Phosphodiesterase Antagonists
- Phosphoric Diester Hydrolase Inhibitors
- Antiphosphodiesterases
|
Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase Inhibitors".
This graph shows the total number of publications written about "Phosphodiesterase Inhibitors" by people in this website by year, and whether "Phosphodiesterase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphodiesterase Inhibitors" by people in Profiles.
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Diabetes induced decreases in PKA signaling in cardiomyocytes: The role of insulin. PLoS One. 2020; 15(8):e0231806.
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Presynaptic ryanodine receptor-activated calmodulin kinase II increases vesicle mobility and potentiates neuropeptide release. J Neurosci. 2007 Jul 18; 27(29):7799-806.
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The postmortem distribution of vardenafil (Levitra) in an aviation accident victim with an unusually high blood concentration. J Anal Toxicol. 2007 Jul-Aug; 31(6):328-33.
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Side effects of using nitrates to treat angina. Expert Opin Drug Saf. 2006 Sep; 5(5):667-74.
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The use of sildenafil in pediatric Takayasu arteritis. Clin Rheumatol. 2006 Jul; 25(4):550.
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Effects of phospholemman downregulation on contractility and [Ca(2+)]i transients in adult rat cardiac myocytes. Am J Physiol Heart Circ Physiol. 2004 Apr; 286(4):H1322-30.
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Sildenafil citrate does not reduce exercise tolerance in men with erectile dysfunction and chronic stable angina. Eur Heart J. 2003 Dec; 24(24):2206-12.
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The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease. J Am Coll Cardiol. 2002 Dec 04; 40(11):2006-12.
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Effects of Na(+)/Ca(2+) exchanger downregulation on contractility and [Ca(2+)](i) transients in adult rat myocytes. Am J Physiol Heart Circ Physiol. 2002 Oct; 283(4):H1616-26.
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Effect of cilostazol in patients with intermittent claudication: a randomized, double-blind, placebo-controlled study. Vasc Endovascular Surg. 2002 Mar-Apr; 36(2):83-91.