Cholinesterase Inhibitors
"Cholinesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Descriptor ID |
D002800
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MeSH Number(s) |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
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Concept/Terms |
Cholinesterase Inhibitors- Cholinesterase Inhibitors
- Inhibitors, Cholinesterase
- Anticholinesterase Drugs
- Drugs, Anticholinesterase
- Anticholinesterases
- Anticholinesterase Agents
- Agents, Anticholinesterase
- Anti-Cholinesterases
- Anti Cholinesterases
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Below are MeSH descriptors whose meaning is more general than "Cholinesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Inhibitors".
This graph shows the total number of publications written about "Cholinesterase Inhibitors" by people in this website by year, and whether "Cholinesterase Inhibitors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 0 | 3 | 3 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cholinesterase Inhibitors" by people in Profiles.
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Cholinesterase Inhibitory Arisugacins L-Q from a Penicillium sp. Isolate Obtained through a Citizen Science Initiative and Their Activities in a Phenotype-Based Zebrafish Assay. J Nat Prod. 2019 09 27; 82(9):2627-2637.
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Pharmacological Management of Dementia with Lewy Bodies. Drugs Aging. 2019 04; 36(4):309-319.
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Polyionic complexes of butyrylcholinesterase and poly-l-lysine-g-poly(ethylene glycol): Comparative kinetics of catalysis and inhibition and in vitro inactivation by proteases and heat. Chem Biol Interact. 2017 Sep 25; 275:86-94.
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Strength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia. Exp Neurol. 2017 09; 295:162-175.
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Postoperative Central Anticholinergic Syndrome: Is it Really that Rare? Am Surg. 2017 Mar 01; 83(3):e104-105.
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In vitro characterization of cationic copolymer-complexed recombinant human butyrylcholinesterase. Biochem Pharmacol. 2015 Dec 01; 98(3):531-9.
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Medications for the treatment of Alzheimer's disease. J Okla State Med Assoc. 2001 Aug; 94(8):347-9.
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What's hot, what's not, in dementia drugs? Part I: Cholinergic therapies. J Gerontol Nurs. 1997 Sep; 23(9):52-4.
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Nuclear magnetic resonance studies on acetylcholinesterase. The use of atropine and eserine to probe binding sites. Mol Pharmacol. 1970 Nov; 6(6):588-96.