"Type C Phospholipases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
| Descriptor ID |
D010738
|
| MeSH Number(s) |
D08.811.277.352.640.700.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Type C Phospholipases".
Below are MeSH descriptors whose meaning is more specific than "Type C Phospholipases".
This graph shows the total number of publications written about "Type C Phospholipases" by people in this website by year, and whether "Type C Phospholipases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 2 | 3 |
| 1998 | 1 | 1 | 2 |
| 1999 | 4 | 1 | 5 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Type C Phospholipases" by people in Profiles.
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Focus on molecules: phosphatidylinositol-4,5-bisphosphate (PIP2). Exp Eye Res. 2010 Sep; 91(3):324-5.
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Alternative splice variants of phospholipase C-beta2 are expressed in platelets: effect on Galphaq-dependent activation and localization. Platelets. 2007 May; 18(3):217-23.
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PKD2 functions as an epidermal growth factor-activated plasma membrane channel. Mol Cell Biol. 2005 Sep; 25(18):8285-98.
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PLCgamma2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells. Eur J Immunol. 2004 Aug; 34(8):2237-47.
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Endosomes, glycosomes, and glycosylphosphatidylinositol catabolism in Leishmania major. J Biol Chem. 2004 Oct 01; 279(40):42106-13.
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Epidermal growth factor activates store-operated Ca2+ channels through an inositol 1,4,5-trisphosphate-independent pathway in human glomerular mesangial cells. J Biol Chem. 2004 Feb 06; 279(6):4570-7.
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Contribution of membrane-damaging toxins to Bacillus endophthalmitis pathogenesis. Infect Immun. 2002 Oct; 70(10):5381-9.
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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med. 2002 Sep 16; 196(6):753-63.
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Convergence of signaling pathways on the activation of ERK in B cells. J Biol Chem. 2002 Jun 28; 277(26):23420-6.
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C-reactive protein induces signaling through Fc gamma RIIa on HL-60 granulocytes. J Immunol. 2002 Feb 01; 168(3):1413-8.