"Thioredoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
Descriptor ID |
D013879
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MeSH Number(s) |
D12.776.915
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thioredoxins".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxins".
This graph shows the total number of publications written about "Thioredoxins" by people in this website by year, and whether "Thioredoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 3 | 4 |
2008 | 1 | 0 | 1 |
2009 | 2 | 0 | 2 |
2010 | 2 | 0 | 2 |
2013 | 1 | 0 | 1 |
2014 | 2 | 0 | 2 |
2015 | 1 | 1 | 2 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thioredoxins" by people in Profiles.
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Antioxidants & bronchopulmonary dysplasia: Beating the system or beating a dead horse? Free Radic Biol Med. 2019 10; 142:138-145.
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Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury. PLoS One. 2017; 12(1):e0168777.
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Thioredoxin interacting protein mediates lipid-induced impairment of glucose uptake in skeletal muscle. Biochem Biophys Res Commun. 2016 Oct 28; 479(4):933-939.
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A novel mouse model for the identification of thioredoxin-1 protein interactions. Free Radic Biol Med. 2016 10; 99:533-543.
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The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR. J Ind Microbiol Biotechnol. 2015 Jun; 42(6):965-9.
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Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell. 2015 Feb 09; 27(2):211-22.
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Thioredoxin-1 redox signaling regulates cell survival in response to hyperoxia. Free Radic Biol Med. 2014 Oct; 75:167-77.
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The thioredoxin system in neonatal lung disease. Antioxid Redox Signal. 2014 Nov 01; 21(13):1916-25.
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Nanoceria and thioredoxin regulate a common antioxidative gene network in tubby mice. Adv Exp Med Biol. 2014; 801:829-36.
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Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2013 Sep; 305(5):L389-95.