"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
|
| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
|
| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 3 | 1 | 4 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 1 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 2 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Reduced estrogen signaling contributes to bone loss and cardiac dysfunction in interleukin-10 knockout mice. Physiol Rep. 2024 Jan; 12(1):e15914.
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Wheat Germ Supplementation Reduces Inflammation and Gut Epithelial Barrier Dysfunction in Female Interleukin-10 Knockout Mice Fed a Pro-Atherogenic Diet. J Nutr. 2023 03; 153(3):870-879.
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals. Front Immunol. 2022; 13:866181.
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Associations Between Smoking and Systemic Lupus Erythematosus-Related Cytokines and Chemokines Among US Female Nurses. Arthritis Care Res (Hoboken). 2021 11; 73(11):1583-1589.
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Peripheral blood interleukin 6, interleukin 10, and T lymphocyte levels are associated with checkpoint inhibitor induced pneumonitis: a case report. Acta Oncol. 2021 06; 60(6):813-817.
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Pegilodecakin as monotherapy or in combination with anti-PD-1 or tyrosine kinase inhibitor in heavily pretreated patients with advanced renal cell carcinoma: Final results of cohorts A, G, H and I of IVY Phase I study. Int J Cancer. 2021 07 15; 149(2):403-408.
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Sex differences in circulating inflammatory mediators as a function of substance use disorder. Drug Alcohol Depend. 2021 04 01; 221:108610.
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Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC). Invest New Drugs. 2021 02; 39(1):182-192.
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Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial. Lancet Oncol. 2019 11; 20(11):1544-1555.
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Acute elevation of serum inflammatory markers predicts symptom recovery after concussion. Neurology. 2019 07 30; 93(5):e497-e507.