A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.

Descriptor ID	D017480
MeSH Number(s)	D12.776.543.750.695.620.775 D12.776.543.750.720.600.610.775 D12.776.543.750.750.555.610.775
Concept/Terms	Receptors, sigma Receptors, sigma sigma Receptors Receptors, sigma Opioid Opioid Receptors, sigma sigma Opioid Receptors Receptors, Opioid, sigma sigma Receptor Receptor, sigma

Below are MeSH descriptors whose meaning is more general than "Receptors, sigma".

Below are MeSH descriptors whose meaning is related to "Receptors, sigma".

Below are MeSH descriptors whose meaning is more specific than "Receptors, sigma".