BH3 Interacting Domain Death Agonist Protein
"BH3 Interacting Domain Death Agonist Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Bcl-2 protein family that reversibly binds MEMBRANES. It is a pro-apoptotic protein that is activated by caspase cleavage.
| Descriptor ID |
D051023
|
| MeSH Number(s) |
D12.644.360.075.718.968 D12.776.476.075.718.937
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "BH3 Interacting Domain Death Agonist Protein".
Below are MeSH descriptors whose meaning is more specific than "BH3 Interacting Domain Death Agonist Protein".
This graph shows the total number of publications written about "BH3 Interacting Domain Death Agonist Protein" by people in this website by year, and whether "BH3 Interacting Domain Death Agonist Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 3 | 0 | 3 |
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Below are the most recent publications written about "BH3 Interacting Domain Death Agonist Protein" by people in Profiles.
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Oligomerization of membrane-bound Bcl-2 is involved in its pore formation induced by tBid. Apoptosis. 2009 Oct; 14(10):1145-53.
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The Bax BH3 peptide H2-H3 promotes apoptosis by inhibiting Bcl-2's pore-forming and anti-Bax activities in the membrane. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Aug; 26(4):829-35.
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The cytosolic domain of Bcl-2 forms small pores in model mitochondrial outer membrane after acidic pH-induced membrane association. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb; 26(1):130-7.
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Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer Res. 2008 Oct 15; 68(20):8573-81.
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A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosis. J Immunol. 2008 Sep 01; 181(5):3077-88.
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Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun. 2007 Nov 30; 363(4):959-64.
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tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation. J Biol Chem. 2006 Nov 24; 281(47):35802-11.