"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure. J Immunotoxicol. 2023 12; 20(1):2148782.
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TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNa production. Cell Immunol. 2020 11; 357:104201.
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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. J Clin Invest. 2017 Apr 03; 127(4):1271-1283.
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Proteome and Secretome Analysis Reveals Differential Post-transcriptional Regulation of Toll-like Receptor Responses. Mol Cell Proteomics. 2017 04; 16(4 suppl 1):S172-S186.
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Phosphoproteome profiling of the macrophage response to different toll-like receptor ligands identifies differences in global phosphorylation dynamics. J Proteome Res. 2014 Nov 07; 13(11):5185-97.
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Loss of DAP12 and FcR? drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCs. PLoS One. 2013; 8(10):e76145.
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Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice. Hepatology. 2013 Aug; 58(2):589-602.
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Interferon-e protects the female reproductive tract from viral and bacterial infection. Science. 2013 Mar 01; 339(6123):1088-92.
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DOK3 negatively regulates LPS responses and endotoxin tolerance. PLoS One. 2012; 7(6):e39967.
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Development of a Grp94 inhibitor. J Am Chem Soc. 2012 Jun 13; 134(23):9796-804.