Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 5 | 1 | 6 |
| 2013 | 5 | 1 | 6 |
| 2014 | 3 | 3 | 6 |
| 2015 | 4 | 0 | 4 |
| 2016 | 2 | 6 | 8 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 3 | 4 |
| 2020 | 2 | 3 | 5 |
| 2021 | 5 | 0 | 5 |
| 2022 | 3 | 2 | 5 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration. Commun Biol. 2024 Sep 02; 7(1):1075.
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Age-related retinal degeneration resulting from the deletion of Shp2 tyrosine phosphatase in photoreceptor neurons. Cell Death Dis. 2024 Aug 08; 15(8):577.
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Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium. Neurobiol Aging. 2024 Aug; 140:41-59.
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Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2311647120.
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DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2022 08 16; 119(33):e2207489119.
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Dependence of Retinal Pigment Epithelium Integrity on the NRF2-Heme Oxygenase-1 Axis. Invest Ophthalmol Vis Sci. 2022 08 02; 63(9):30.
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Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient With Fragile X Syndrome. J Pediatr Ophthalmol Strabismus. 2022 Jul-Aug; 59(4):e39-e41.
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Prph2 disease mutations lead to structural and functional defects in the RPE. FASEB J. 2022 05; 36(5):e22284.
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Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration. Cell Death Dis. 2022 Mar 21; 13(3):255.
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Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Aging Cell. 2022 04; 21(4):e13579.