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Hiroshi Yamada

TitleProf,Asst of Research
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentMedicine Hematology/Oncology
AddressBRC 1203
975 NE 10th St
Oklahoma City OK 73104
Phone405/271-8001 ext 32524
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yamada HY, Xu C, Jones KL, O'Neill PH, Venkateshwar M, Chiliveru S, Kim HG, Doescher M, Morris KT, Manne U, Rao CV. Molecular disparities in colorectal cancers of White Americans, Alabama African Americans, and Oklahoma American Indians. NPJ Precis Oncol. 2023 Aug 19; 7(1):79. PMID: 37598287; PMCID: PMC10439889.
      Citations:    
    2. Rao CV, Xu C, Zhang Y, Asch AS, Yamada HY. Genomic instability genes in lung and colon adenocarcinoma indicate organ specificity of transcriptomic impact on Copy Number Alterations. Sci Rep. 2022 07 11; 12(1):11739. PMID: 35817785.
      Citations:    Fields:    Translation:HumansCells
    3. Rao CV, Yamada HY. How would preclinical Alzheimer's disease (AD pathology) occur? An insight from a genomic instability mouse model. Neural Regen Res. 2021 Oct; 16(10):2012-2014. PMID: 33642383.
      Citations: 1     
    4. Rao CV, Xu C, Farooqui M, Zhang Y, Asch AS, Yamada HY. Survival-Critical Genes Associated with Copy Number Alterations in Lung Adenocarcinoma. Cancers (Basel). 2021 May 25; 13(11). PMID: 34070461.
      Citations: 1     
    5. Rao CV, Farooqui M, Madhavaram A, Zhang Y, Asch AS, Yamada HY. GSK3-ARC/Arg3.1 and GSK3-Wnt signaling axes trigger amyloid-ß accumulation and neuroinflammation in middle-aged Shugoshin 1 mice. Aging Cell. 2020 10; 19(10):e13221. PMID: 32857910.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    6. Rao CV, Asch AS, Carr DJJ, Yamada HY. "Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease. Aging Cell. 2020 03; 19(3):e13109. PMID: 31981470.
      Citations: 22     Fields:    Translation:HumansAnimals
    7. Rao CV, Farooqui M, Asch AS, Yamada HY. Critical role of mitosis in spontaneous late-onset Alzheimer's disease; from a Shugoshin 1 cohesinopathy mouse model. Cell Cycle. 2018; 17(19-20):2321-2334. PMID: 30231670.
      Citations: 4     Fields:    Translation:Animals
    8. Rao CV, Farooqui M, Zhang Y, Asch AS, Yamada HY. Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model. Aging Cell. 2018 08; 17(4):e12797. PMID: 29943428.
      Citations: 15     Fields:    Translation:Animals
    9. Rao CV, Pal S, Mohammed A, Farooqui M, Doescher MP, Asch AS, Yamada HY. Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damage in vivo. Oncotarget. 2017 Aug 22; 8(34):57605-57621. PMID: 28915699.
      Citations: 24     Fields:    
    10. Rao CV, Asch AS, Yamada HY. Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer. Carcinogenesis. 2017 01; 38(1):2-11. PMID: 27838634.
      Citations: 66     Fields:    Translation:HumansCells
    11. Rao CV, Asch AS, Yamada HY. Emerging links among Chromosome Instability (CIN), cancer, and aging. Mol Carcinog. 2017 03; 56(3):791-803. PMID: 27533343.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    12. Yamada HY, Kumar G, Zhang Y, Rubin E, Lightfoot S, Dai W, Rao CV. Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung. Oncogenesis. 2016 Aug 15; 5(8):e256. PMID: 27526110.
      Citations: 10     
    13. Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Janakiram NB, Mohammed A, Dai W, Yamada HY. Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ Mice. Cancer Res. 2016 Feb 01; 76(3):630-42. PMID: 26833665.
      Citations: 13     Fields:    Translation:Animals
    14. Mohammed A, Janakiram NB, Madka V, Brewer M, Ritchie RL, Lightfoot S, Kumar G, Sadeghi M, Patlolla JM, Yamada HY, Cruz-Monserrate Z, May R, Houchen CW, Steele VE, Rao CV. Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression. Oncotarget. 2015 Jun 20; 6(17):15524-39. PMID: 25906749.
      Citations: 26     Fields:    Translation:AnimalsCells
    15. Rao CV, Sanghera S, Zhang Y, Biddick L, Reddy A, Lightfoot S, Dai W, Yamada HY. Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability model. Mol Carcinog. 2016 May; 55(5):600-10. PMID: 25773652.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    16. Yamada HY, Zhang Y, Reddy A, Mohammed A, Lightfoot S, Dai W, Rao CV. Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient mice. Carcinogenesis. 2015 Apr; 36(4):429-40. PMID: 25740822.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    17. Rao CV, Yamada HY. Genomic instability and colon carcinogenesis: from the perspective of genes. Front Oncol. 2013; 3:130. PMID: 23734346.
      Citations: 41     
    18. Rao CV, Kurkjian CD, Yamada HY. Mitosis-targeting natural products for cancer prevention and therapy. Curr Drug Targets. 2012 Dec; 13(14):1820-30. PMID: 23140292.
      Citations: 21     Fields:    Translation:HumansAnimals
    19. Yamada HY, Yao Y, Wang X, Zhang Y, Huang Y, Dai W, Rao CV. Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle. 2012 Feb 01; 11(3):479-88. PMID: 22262168.
      Citations: 43     Fields:    Translation:AnimalsCells
    20. Yamada HY, Rao CV. Genes that modulate the sensitivity for anti-microtubule drug-mediated chemotherapy. Curr Cancer Drug Targets. 2010 Sep; 10(6):623-33. PMID: 20491618.
      Citations: 5     Fields:    Translation:HumansCells
    21. Yamada HY, Rao CV. BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy. Int J Oncol. 2009 Nov; 35(5):1101-9. PMID: 19787264.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    22. Rao CV, Yamada HY, Yao Y, Dai W. Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice. Carcinogenesis. 2009 Sep; 30(9):1469-74. PMID: 19372138.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    23. Yamada HY, Gorbsky GJ. Spindle checkpoint function and cellular sensitivity to antimitotic drugs. Mol Cancer Ther. 2006 Dec; 5(12):2963-9. PMID: 17172401.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    24. Yamada HY, Gorbsky GJ. Cell-based expression cloning for identification of polypeptides that hypersensitize mammalian cells to mitotic arrest. Biol Proced Online. 2006; 8:36-43. PMID: 16799695.
      Citations: 1     
    25. Yamada HY, Gorbsky GJ. Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105. Oncogene. 2006 Mar 02; 25(9):1330-9. PMID: 16314844.
      Citations: 13     Fields:    Translation:HumansCells
    26. Yamada HY, Gorbsky GJ. Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons. Mol Cancer Ther. 2006 Jan; 5(1):29-38. PMID: 16432160.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    27. Yamada HY, Matsumoto S, Matsumoto T. High dosage expression of a zinc finger protein, Grt1, suppresses a mutant of fission yeast slp1(+), a homolog of CDC20/p55CDC/Fizzy. J Cell Sci. 2000 Nov; 113 ( Pt 22):3989-99. PMID: 11058086.
      Citations: 9     Fields:    Translation:AnimalsCells
    28. Yamada H, Kumada K, Yanagida M. Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. J Cell Sci. 1997 Aug; 110 ( Pt 15):1793-804. PMID: 9264466.
      Citations: 55     Fields:    Translation:AnimalsCells
    29. Yamashita YM, Nakaseko Y, Samejima I, Kumada K, Yamada H, Michaelson D, Yanagida M. 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway. Nature. 1996 Nov 21; 384(6606):276-9. PMID: 8918880.
      Citations: 55     Fields:    Translation:Animals
    30. Takahashi K, Yamada H, Yanagida M. Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality. Mol Biol Cell. 1994 Oct; 5(10):1145-58. PMID: 7865880; PMCID: PMC301137.
      Citations: 95     Fields:    Translation:AnimalsCells
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