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Padmaja Dhanasekaran

TitleSr Lab Rsrch Mgr
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentStephenson Cancer Center
AddressBRC 1466
975 NE 10th St
Oklahoma City OK 73104
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ha JH, Jayaraman M, Yan M, Dhanasekaran P, Isidoro C, Song YS, Dhanasekaran DN. GNAi2/gip2-Regulated Transcriptome and Its Therapeutic Significance in Ovarian Cancer. Biomolecules. 2021 08 14; 11(8). PMID: 34439877.
      Citations: 7     Fields:    Translation:HumansCells
    2. Ha JH, Jayaraman M, Yan M, Dhanasekaran P, Isidoro C, Song YS, Dhanasekaran DN. Identification of GNA12-driven gene signatures and key signaling networks in ovarian cancer. Oncol Lett. 2021 Oct; 22(4):719. PMID: 34429759.
      Citations: 2     
    3. Mizuguchi C, Hata M, Dhanasekaran P, Nickel M, Okuhira K, Phillips MC, Lund-Katz S, Saito H. Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4. Biochim Biophys Acta. 2014 Dec; 1841(12):1716-24. PMID: 25281910.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    4. Nguyen D, Dhanasekaran P, Nickel M, Mizuguchi C, Watanabe M, Saito H, Phillips MC, Lund-Katz S. Influence of domain stability on the properties of human apolipoprotein E3 and E4 and mouse apolipoprotein E. Biochemistry. 2014 Jun 24; 53(24):4025-33. PMID: 24871385.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    5. Nagao K, Hata M, Tanaka K, Takechi Y, Nguyen D, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H. The roles of C-terminal helices of human apolipoprotein A-I in formation of high-density lipoprotein particles. Biochim Biophys Acta. 2014 Jan; 1841(1):80-7. PMID: 24120703.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    6. Li H, Dhanasekaran P, Alexander ET, Rader DJ, Phillips MC, Lund-Katz S. Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels. Arterioscler Thromb Vasc Biol. 2013 Apr; 33(4):687-93. PMID: 23413428.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    7. Adachi E, Nakajima H, Mizuguchi C, Dhanasekaran P, Kawashima H, Nagao K, Akaji K, Lund-Katz S, Phillips MC, Saito H. Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation. J Biol Chem. 2013 Jan 25; 288(4):2848-56. PMID: 23233678.
      Citations: 15     Fields:    Translation:HumansCells
    8. Chetty PS, Ohshiro M, Saito H, Dhanasekaran P, Lund-Katz S, Mayne L, Englander W, Phillips MC. Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry. Biochemistry. 2012 Nov 06; 51(44):8993-9001. PMID: 23066790.
      Citations: 17     Fields:    Translation:HumansCells
    9. Mizuguchi C, Hata M, Dhanasekaran P, Nickel M, Phillips MC, Lund-Katz S, Saito H. Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4. Biochemistry. 2012 Jul 17; 51(28):5580-8. PMID: 22730894.
      Citations: 11     Fields:    Translation:HumansCells
    10. Lyssenko NN, Hata M, Dhanasekaran P, Nickel M, Nguyen D, Chetty PS, Saito H, Lund-Katz S, Phillips MC. Influence of C-terminal a-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality. Biochim Biophys Acta. 2012 Mar; 1821(3):456-63. PMID: 21840419.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    11. Nguyen D, Dhanasekaran P, Nickel M, Nakatani R, Saito H, Phillips MC, Lund-Katz S. Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4. Biochemistry. 2010 Dec 28; 49(51):10881-9. PMID: 21114327.
      Citations: 43     Fields:    Translation:HumansCells
    12. Tanaka M, Dhanasekaran P, Nguyen D, Nickel M, Takechi Y, Lund-Katz S, Phillips MC, Saito H. Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I. Biochim Biophys Acta. 2011 Jan; 1811(1):25-30. PMID: 21040803.
      Citations: 14     Fields:    Translation:HumansCells
    13. Vedhachalam C, Chetty PS, Nickel M, Dhanasekaran P, Lund-Katz S, Rothblat GH, Phillips MC. Influence of apolipoprotein (Apo) A-I structure on nascent high density lipoprotein (HDL) particle size distribution. J Biol Chem. 2010 Oct 15; 285(42):31965-73. PMID: 20679346.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    14. Kono M, Tanaka T, Tanaka M, Vedhachalam C, Chetty PS, Nguyen D, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H. Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan. J Lipid Res. 2010 Apr; 51(4):809-18. PMID: 19805625.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    15. Lund-Katz S, Nguyen D, Dhanasekaran P, Kono M, Nickel M, Saito H, Phillips MC. Surface plasmon resonance analysis of the mechanism of binding of apoA-I to high density lipoprotein particles. J Lipid Res. 2010 Mar; 51(3):606-17. PMID: 19786567.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    16. Nguyen DV, Drover VA, Knopfel M, Dhanasekaran P, Hauser H, Phillips MC. Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption. J Lipid Res. 2009 Nov; 50(11):2235-44. PMID: 19454765.
      Citations: 19     Fields:    Translation:AnimalsCells
    17. Nguyen D, Dhanasekaran P, Phillips MC, Lund-Katz S. Molecular mechanism of apolipoprotein E binding to lipoprotein particles. Biochemistry. 2009 Apr 07; 48(13):3025-32. PMID: 19209940.
      Citations: 32     Fields:    Translation:HumansCells
    18. Koyama M, Tanaka M, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H. Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I. Biochemistry. 2009 Mar 24; 48(11):2529-37. PMID: 19239199.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    19. Kono M, Okumura Y, Tanaka M, Nguyen D, Dhanasekaran P, Lund-Katz S, Phillips MC, Saito H. Conformational flexibility of the N-terminal domain of apolipoprotein a-I bound to spherical lipid particles. Biochemistry. 2008 Oct 28; 47(43):11340-7. PMID: 18831538.
      Citations: 30     Fields:    Translation:HumansCells
    20. Yamauchi Y, Deguchi N, Takagi C, Tanaka M, Dhanasekaran P, Nakano M, Handa T, Phillips MC, Lund-Katz S, Saito H. Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: a surface plasmon resonance study. Biochemistry. 2008 Jun 24; 47(25):6702-10. PMID: 18507396.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    21. Tanaka M, Koyama M, Dhanasekaran P, Nguyen D, Nickel M, Lund-Katz S, Saito H, Phillips MC. Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I. Biochemistry. 2008 Feb 19; 47(7):2172-80. PMID: 18205410.
      Citations: 29     Fields:    Translation:AnimalsCells
    22. Sakamoto T, Tanaka M, Vedhachalam C, Nickel M, Nguyen D, Dhanasekaran P, Phillips MC, Lund-Katz S, Saito H. Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms. Biochemistry. 2008 Mar 04; 47(9):2968-77. PMID: 18201068.
      Citations: 35     Fields:    Translation:HumansCells
    23. Vedhachalam C, Duong PT, Nickel M, Nguyen D, Dhanasekaran P, Saito H, Rothblat GH, Lund-Katz S, Phillips MC. Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles. J Biol Chem. 2007 Aug 24; 282(34):25123-30. PMID: 17604270.
      Citations: 167     Fields:    Translation:AnimalsCells
    24. Tanaka M, Dhanasekaran P, Nguyen D, Ohta S, Lund-Katz S, Phillips MC, Saito H. Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I. Biochemistry. 2006 Aug 29; 45(34):10351-8. PMID: 16922511.
      Citations: 37     Fields:    Translation:HumansCells
    25. Tanaka M, Vedhachalam C, Sakamoto T, Dhanasekaran P, Phillips MC, Lund-Katz S, Saito H. Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4. Biochemistry. 2006 Apr 04; 45(13):4240-7. PMID: 16566598.
      Citations: 29     Fields:    Translation:HumansCells
    26. Tanaka M, Saito H, Dhanasekaran P, Wehrli S, Handa T, Lund-Katz S, Phillips MC. Effects of the core lipid on the energetics of binding of ApoA-I to model lipoprotein particles of different sizes. Biochemistry. 2005 Aug 09; 44(31):10689-95. PMID: 16060677.
      Citations: 3     Fields:    Translation:HumansCells
    27. Futamura M, Dhanasekaran P, Handa T, Phillips MC, Lund-Katz S, Saito H. Two-step mechanism of binding of apolipoprotein E to heparin: implications for the kinetics of apolipoprotein E-heparan sulfate proteoglycan complex formation on cell surfaces. J Biol Chem. 2005 Feb 18; 280(7):5414-22. PMID: 15583000.
      Citations: 48     Fields:    Translation:HumansCells
    28. Vedhachalam C, Liu L, Nickel M, Dhanasekaran P, Anantharamaiah GM, Lund-Katz S, Rothblat GH, Phillips MC. Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids. J Biol Chem. 2004 Nov 26; 279(48):49931-9. PMID: 15383537.
      Citations: 42     Fields:    Translation:HumansCells
    29. Saito H, Dhanasekaran P, Nguyen D, Deridder E, Holvoet P, Lund-Katz S, Phillips MC. Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids. J Biol Chem. 2004 May 14; 279(20):20974-81. PMID: 15020600.
      Citations: 51     Fields:    Translation:HumansCells
    30. Narayanaswami V, Maiorano JN, Dhanasekaran P, Ryan RO, Phillips MC, Lund-Katz S, Davidson WS. Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles. J Biol Chem. 2004 Apr 02; 279(14):14273-9. PMID: 14739281.
      Citations: 37     Fields:    Translation:HumansCells
    31. Thuahnai ST, Lund-Katz S, Dhanasekaran P, de la Llera-Moya M, Connelly MA, Williams DL, Rothblat GH, Phillips MC. Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure. J Biol Chem. 2004 Mar 26; 279(13):12448-55. PMID: 14718538.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    32. Liu L, Bortnick AE, Nickel M, Dhanasekaran P, Subbaiah PV, Lund-Katz S, Rothblat GH, Phillips MC. Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles. J Biol Chem. 2003 Oct 31; 278(44):42976-84. PMID: 12928428.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    33. Saito H, Dhanasekaran P, Baldwin F, Weisgraber KH, Phillips MC, Lund-Katz S. Effects of polymorphism on the lipid interaction of human apolipoprotein E. J Biol Chem. 2003 Oct 17; 278(42):40723-9. PMID: 12917433.
      Citations: 41     Fields:    Translation:HumansCells
    34. Saito H, Dhanasekaran P, Nguyen D, Holvoet P, Lund-Katz S, Phillips MC. Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model. J Biol Chem. 2003 Jun 27; 278(26):23227-32. PMID: 12709430.
      Citations: 82     Fields:    Translation:HumansCells
    35. Saito H, Dhanasekaran P, Nguyen D, Baldwin F, Weisgraber KH, Wehrli S, Phillips MC, Lund-Katz S. Characterization of the heparin binding sites in human apolipoprotein E. J Biol Chem. 2003 Apr 25; 278(17):14782-7. PMID: 12588864.
      Citations: 45     Fields:    Translation:HumansCells
    36. Segall ML, Dhanasekaran P, Baldwin F, Anantharamaiah GM, Weisgraber KH, Phillips MC, Lund-Katz S. Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization. J Lipid Res. 2002 Oct; 43(10):1688-700. PMID: 12364553.
      Citations: 42     Fields:    Translation:Cells
    37. Saito H, Dhanasekaran P, Baldwin F, Weisgraber KH, Lund-Katz S, Phillips MC. Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles. J Biol Chem. 2001 Nov 02; 276(44):40949-54. PMID: 11533033.
      Citations: 48     Fields:    Translation:HumansCells
    38. Lund-Katz S, Zaiou M, Wehrli S, Dhanasekaran P, Baldwin F, Weisgraber KH, Phillips MC. Effects of lipid interaction on the lysine microenvironments in apolipoprotein E. J Biol Chem. 2000 Nov 03; 275(44):34459-64. PMID: 10921925.
      Citations: 18     Fields:    Translation:Cells
    39. Piddington R, Joyce J, Dhanasekaran P, Baker L. Diabetes mellitus affects prostaglandin E2 levels in mouse embryos during neurulation. Diabetologia. 1996 Aug; 39(8):915-20. PMID: 8858213.
      Citations: 13     Fields:    Translation:Animals
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