"Apolipoprotein E3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.
| Descriptor ID |
D053318
|
| MeSH Number(s) |
D10.532.091.500.500 D12.776.070.400.500.500 D12.776.521.120.500.500
|
| Concept/Terms |
Apolipoprotein E3- Apolipoprotein E3
- Apo E3
- APOE-epsilon 3
- APOE epsilon 3
- Isoapolipoprotein E3
- ApoE3
- Apolipoprotein E-3
- Apolipoprotein E 3
- Apolipoprotein E-epsilon3
- Apolipoprotein E epsilon3
- Apo E-3
- Apo E 3
- APOE-epsilon3
- APOE epsilon3
|
Below are MeSH descriptors whose meaning is more general than "Apolipoprotein E3".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein E3".
This graph shows the total number of publications written about "Apolipoprotein E3" by people in this website by year, and whether "Apolipoprotein E3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Apolipoprotein E3" by people in Profiles.
-
Cyclic O3 exposure synergizes with aging leading to memory impairment in male APOE e3, but not APOE e4, targeted replacement mice. Neurobiol Aging. 2019 09; 81:9-21.
-
Association of APOE polymorphisms with diabetes and cardiometabolic risk factors and the role of APOE genotypes in response to anti-diabetic therapy: results from the AIDHS/SDS on a South Asian population. J Diabetes Complications. 2015 Nov-Dec; 29(8):1191-7.
-
Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4. Biochim Biophys Acta. 2014 Dec; 1841(12):1716-24.
-
Influence of domain stability on the properties of human apolipoprotein E3 and E4 and mouse apolipoprotein E. Biochemistry. 2014 Jun 24; 53(24):4025-33.
-
Neuroprotective Sirtuin ratio reversed by ApoE4. Proc Natl Acad Sci U S A. 2013 Nov 05; 110(45):18303-8.
-
Molecular mechanisms responsible for the differential effects of apoE3 and apoE4 on plasma lipoprotein-cholesterol levels. Arterioscler Thromb Vasc Biol. 2013 Apr; 33(4):687-93.
-
Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4. Biochemistry. 2010 Dec 28; 49(51):10881-9.
-
Molecular mechanism of apolipoprotein E binding to lipoprotein particles. Biochemistry. 2009 Apr 07; 48(13):3025-32.
-
Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: a surface plasmon resonance study. Biochemistry. 2008 Jun 24; 47(25):6702-10.
-
Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms. Biochemistry. 2008 Mar 04; 47(9):2968-77.