"Neuropilin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
| Descriptor ID |
D039942
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| MeSH Number(s) |
D12.776.543.750.590.500
|
| Concept/Terms |
Neuropilin-1- Neuropilin-1
- Neuropilin 1
- Sema III Receptor
- Receptor, Sema III
- NRP1 Protein
- Semaphorin III Receptor
- A5 Antigen
- Antigen, A5
- Npn-1 Protein
- Npn 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Neuropilin-1".
Below are MeSH descriptors whose meaning is more specific than "Neuropilin-1".
This graph shows the total number of publications written about "Neuropilin-1" by people in this website by year, and whether "Neuropilin-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuropilin-1" by people in Profiles.
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Maternal plasma soluble neuropilin-1 is downregulated in fetal growth restriction complicated by abnormal umbilical artery Doppler: a pilot study. Ultrasound Obstet Gynecol. 2021 Nov; 58(5):716-721.
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Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses. J Natl Cancer Inst. 2017 11 01; 109(11).
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Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers. Oncotarget. 2016 Feb 16; 7(7):7970-8.
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Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res. 2010 Jun 25; 106(12):1893-903.