A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.

Descriptor ID	D040501
MeSH Number(s)	D12.776.157.125.750.500.100 D12.776.631.655.500.100 D23.050.301.562.100
Concept/Terms	Calgranulin A Calgranulin A 60B8-B Antigen 60B8 B Antigen Antigen, 60B8-B CABP-P8 MRP8 Protein Leukocyte L1 Protein Light Chain Myeloid Calcium-Binding Protein P8 Myeloid Calcium Binding Protein P8 MRP-8 Protein MRP 8 Protein S100 A8 Protein A8 Protein, S100 S100A8 Protein Cystic Fibrosis Antigen Antigen, Cystic Fibrosis Macrophage-Related Protein-8 Macrophage Related Protein 8

Below are MeSH descriptors whose meaning is more general than "Calgranulin A".

Below are MeSH descriptors whose meaning is related to "Calgranulin A".

Below are MeSH descriptors whose meaning is more specific than "Calgranulin A".