"Insulin-Secreting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.
| Descriptor ID |
D050417
|
| MeSH Number(s) |
A03.734.414.131 A06.390.131 A06.407.414.087 A11.382.625.092 A11.436.294.092
|
| Concept/Terms |
Insulin-Secreting Cells- Insulin-Secreting Cells
- Cell, Insulin-Secreting
- Cells, Insulin-Secreting
- Insulin Secreting Cells
- Insulin-Secreting Cell
- beta Cells, Pancreatic
- Pancreatic beta Cell
- beta Cell, Pancreatic
- Pancreatic B Cells
- B Cell, Pancreatic
- B Cells, Pancreatic
- Pancreatic B Cell
- Pancreatic beta Cells
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Secreting Cells".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Secreting Cells".
This graph shows the total number of publications written about "Insulin-Secreting Cells" by people in this website by year, and whether "Insulin-Secreting Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin-Secreting Cells" by people in Profiles.
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Hydroxybenzamide derivatives protect pancreatic ß cell by suppressing unfolded protein response activation. Chem Biol Drug Des. 2022 08; 100(2):155-168.
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Pharmacological Inhibition of Inositol-Requiring Enzyme 1a RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes. Front Endocrinol (Lausanne). 2021; 12:749879.
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A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 07 03; 295(27):8901-8911.
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Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure. Pediatr Diabetes. 2020 06; 21(4):575-585.
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Discovery of N-(2-(Benzylamino)-2-oxoethyl)benzamide analogs as a novel scaffold of pancreatic ß-cell protective agents against endoplasmic reticulum stress. Chem Biol Drug Des. 2020 03; 95(3):388-393.
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The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in ß-Cell Function in TODAY. Diabetes Care. 2019 01; 42(1):164-172.
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Discovery of a Benzamide Derivative That Protects Pancreatic ß-Cells against Endoplasmic Reticulum Stress. J Med Chem. 2017 07 27; 60(14):6191-6204.
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Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic ß-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress. J Med Chem. 2016 09 08; 59(17):7783-800.
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Identification of 1,2,3-triazole derivatives that protect pancreatic ß cells against endoplasmic reticulum stress-mediated dysfunction and death through the inhibition of C/EBP-homologous protein expression. Bioorg Med Chem. 2016 06 15; 24(12):2621-30.
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Relationship Between Parental Diabetes and Presentation of Metabolic and Glycemic Function in Youth With Type 2 Diabetes: Baseline Findings From the TODAY Trial. Diabetes Care. 2016 Jan; 39(1):110-7.