"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 1995 | 4 | 5 | 9 |
| 1996 | 1 | 3 | 4 |
| 1997 | 1 | 2 | 3 |
| 1998 | 4 | 4 | 8 |
| 1999 | 2 | 3 | 5 |
| 2000 | 0 | 3 | 3 |
| 2001 | 4 | 5 | 9 |
| 2002 | 6 | 7 | 13 |
| 2003 | 5 | 8 | 13 |
| 2004 | 2 | 5 | 7 |
| 2005 | 3 | 10 | 13 |
| 2006 | 3 | 3 | 6 |
| 2007 | 3 | 3 | 6 |
| 2008 | 1 | 8 | 9 |
| 2009 | 3 | 8 | 11 |
| 2010 | 0 | 4 | 4 |
| 2011 | 3 | 6 | 9 |
| 2012 | 5 | 5 | 10 |
| 2013 | 1 | 5 | 6 |
| 2014 | 5 | 5 | 10 |
| 2015 | 5 | 4 | 9 |
| 2016 | 4 | 2 | 6 |
| 2017 | 1 | 6 | 7 |
| 2018 | 1 | 7 | 8 |
| 2019 | 5 | 5 | 10 |
| 2020 | 1 | 3 | 4 |
| 2021 | 4 | 9 | 13 |
| 2022 | 3 | 3 | 6 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 3 | 4 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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A mixed meal tolerance test predicts onset of type 2 diabetes in Southwestern Indigenous adults. Nutr Diabetes. 2024 07 10; 14(1):50.
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Phylogenetic and transcriptomic characterization of insulin and growth factor receptor tyrosine kinases in crustaceans. Front Endocrinol (Lausanne). 2024; 15:1379231.
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Loss of Cardiac PFKFB2 Drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart. J Am Heart Assoc. 2024 Apr 02; 13(7):e033676.
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Role of human Kallistatin in glucose and energy homeostasis in mice. Mol Metab. 2024 Apr; 82:101905.
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Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats. Nutrients. 2023 Oct 19; 15(20).
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Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth. Adv Sci (Weinh). 2022 11; 9(31):e2200491.
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Poly-L-lysine Coated Oral Nanoemulsion for Combined Delivery of Insulin and C-Peptide. J Pharm Sci. 2022 Dec; 111(12):3352-3361.
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A maternal higher-complex carbohydrate diet increases bifidobacteria and alters early life acquisition of the infant microbiome in women with gestational diabetes mellitus. Front Endocrinol (Lausanne). 2022; 13:921464.
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Cullin neddylation inhibitor attenuates hyperglycemia by enhancing hepatic insulin signaling through insulin receptor substrate stabilization. Proc Natl Acad Sci U S A. 2022 02 08; 119(6).
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Impact of food processing on postprandial glycaemic and appetite responses in healthy adults: a randomized, controlled trial. Food Funct. 2022 Feb 07; 13(3):1280-1290.