"Retinal Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloflavoprotein enzyme involved the metabolism of VITAMIN A, this enzyme catalyzes the oxidation of RETINAL to RETINOIC ACID, using both NAD+ and FAD coenzymes. It also acts on both the 11-trans- and 13-cis-forms of RETINAL.
| Descriptor ID |
D050697
|
| MeSH Number(s) |
D08.811.682.657.163.835 D12.776.331.915 D12.776.556.579.374.687
|
| Concept/Terms |
Retinal Dehydrogenase- Retinal Dehydrogenase
- Dehydrogenase, Retinal
- Cytosolic Retinal Dehydrogenase
- Dehydrogenase, Cytosolic Retinal
- Retinal Dehydrogenase, Cytosolic
|
Below are MeSH descriptors whose meaning is more general than "Retinal Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Retinal Dehydrogenase".
This graph shows the total number of publications written about "Retinal Dehydrogenase" by people in this website by year, and whether "Retinal Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinal Dehydrogenase" by people in Profiles.
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3D-QSAR and scaffold hopping based designing of benzo[d]ox-azol-2(3H)-one and 2-oxazolo[4,5-b]pyridin-2(3H)-one derivatives as selective aldehyde dehydrogenase 1A1 inhibitors: Synthesis and biological evaluation. Arch Pharm (Weinheim). 2022 Sep; 355(9):e2200108.
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Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia. Commun Biol. 2020 11 19; 3(1):693.
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Metabolomic Studies of Live Single Cancer Stem Cells Using Mass Spectrometry. Anal Chem. 2019 02 05; 91(3):2384-2391.
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Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem. 2018 12 01; 26(22):5766-5779.
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Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. PLoS One. 2015; 10(3):e0122008.
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ß-Escin inhibits NNK-induced lung adenocarcinoma and ALDH1A1 and RhoA/Rock expression in A/J mice and growth of H460 human lung cancer cells. Cancer Prev Res (Phila). 2013 Oct; 6(10):1140-9.
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Carcinine has 4-hydroxynonenal scavenging property and neuroprotective effect in mouse retina. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3572-83.
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Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. Invest Ophthalmol Vis Sci. 2008 Mar; 49(3):1071-8.