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UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
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UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.
UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Mol Cancer Ther. 2013 Nov; 12(11):2367-77.
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PubMed
subject areas
Animals
Animals
Animals, Genetically Modified
Animals, Genetically Modified
Antineoplastic Agents
Antineoplastic Agents
Cell Line, Tumor
Cell Line, Tumor
c-Mer Tyrosine Kinase
c-Mer Tyrosine Kinase
Gene Expression Regulation, Leukemic
Gene Expression Regulation, Leukemic
Humans
Humans
Jurkat Cells
Jurkat Cells
MAP Kinase Signaling System
MAP Kinase Signaling System
Molecular Targeted Therapy
Molecular Targeted Therapy
Neoplasms, Experimental
Neoplasms, Experimental
Phosphorylation
Phosphorylation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Proto-Oncogene Proteins
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-akt
Pyrazoles
Pyrazoles
Pyrimidines
Pyrimidines
Receptor Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Rhabdoid Tumor
Rhabdoid Tumor
Teratoma
Teratoma
Zebrafish
Zebrafish
authors with profiles
John Kimble Frazer