UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo.

UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. Mol Cancer Ther. 2013 Nov; 12(11):2367-77.

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subject areas

Animals
Animals, Genetically Modified
Antineoplastic Agents
Cell Line, Tumor
c-Mer Tyrosine Kinase
Gene Expression Regulation, Leukemic
Humans
Jurkat Cells
MAP Kinase Signaling System
Molecular Targeted Therapy
Neoplasms, Experimental
Phosphorylation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Pyrazoles
Pyrimidines
Receptor Protein-Tyrosine Kinases
Rhabdoid Tumor
Teratoma
Zebrafish

authors with profiles

John Kimble Frazer