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A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.
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A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.
A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. Nat Genet. 2017 Sep; 49(9):1326-1335.
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PubMed
subject areas
Base Sequence
Base Sequence
Cell Line, Tumor
Cell Line, Tumor
Cell Proliferation
Cell Proliferation
Cell Transformation, Neoplastic
Cell Transformation, Neoplastic
Cells, Cultured
Cells, Cultured
Cellular Senescence
Cellular Senescence
Gene Expression Profiling
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Neoplastic
Humans
Humans
Immunoblotting
Immunoblotting
INDEL Mutation
INDEL Mutation
Introns
Introns
Melanocytes
Melanocytes
Melanoma
Melanoma
Microphthalmia-Associated Transcription Factor
Microphthalmia-Associated Transcription Factor
Microscopy, Confocal
Microscopy, Confocal
Poly (ADP-Ribose) Polymerase-1
Poly (ADP-Ribose) Polymerase-1
Polymorphism, Single Nucleotide
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins B-raf
Risk Factors
Risk Factors
Telomerase
Telomerase
authors with profiles
Kevin Michael Brown