"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
|
| MeSH Number(s) |
D12.644.456.448
|
| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
|
Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 5 | 5 |
| 2010 | 0 | 6 | 6 |
| 2011 | 2 | 2 | 4 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 3 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 4 | 4 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity. Biochem Pharmacol. 2024 Apr; 222:116103.
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Long-term methamphetamine self-administration increases mesolimbic mitochondrial oxygen consumption and decreases striatal glutathione. Neuropharmacology. 2023 04 01; 227:109436.
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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis. Nat Commun. 2022 09 28; 13(1):5696.
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Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice. Redox Biol. 2021 01; 38:101797.
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A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. J Med Chem. 2020 09 10; 63(17):9838-9855.
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Selenium-independent antioxidant and anti-inflammatory effects of thioredoxin reductase inhibition in alveolar macrophages. Life Sci. 2020 Oct 15; 259:118285.
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Aurothioglucose enhances proangiogenic pathway activation in lungs from room air and hyperoxia-exposed newborn mice. Am J Physiol Lung Cell Mol Physiol. 2020 06 01; 318(6):L1165-L1171.
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Vitamin E modifies high-fat diet-induced reduction of seizure threshold in rats: Role of oxidative stress. Physiol Behav. 2019 07 01; 206:200-205.
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Antioxidants & bronchopulmonary dysplasia: Beating the system or beating a dead horse? Free Radic Biol Med. 2019 10; 142:138-145.
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Oxygenated Preservation Solutions for Organ Preservation. Transplantation. 2019 02; 103(2):233-234.