Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
|
| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
|
| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 3 | 4 |
| 1995 | 7 | 2 | 9 |
| 1996 | 4 | 2 | 6 |
| 1997 | 3 | 2 | 5 |
| 1998 | 4 | 2 | 6 |
| 1999 | 4 | 3 | 7 |
| 2000 | 5 | 3 | 8 |
| 2001 | 4 | 5 | 9 |
| 2002 | 9 | 3 | 12 |
| 2003 | 1 | 3 | 4 |
| 2004 | 2 | 5 | 7 |
| 2005 | 8 | 5 | 13 |
| 2006 | 6 | 1 | 7 |
| 2007 | 1 | 6 | 7 |
| 2008 | 2 | 4 | 6 |
| 2009 | 6 | 3 | 9 |
| 2010 | 2 | 2 | 4 |
| 2011 | 6 | 5 | 11 |
| 2012 | 2 | 3 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 3 | 3 | 6 |
| 2015 | 3 | 1 | 4 |
| 2016 | 4 | 4 | 8 |
| 2017 | 3 | 2 | 5 |
| 2018 | 1 | 5 | 6 |
| 2019 | 3 | 0 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 3 | 1 | 4 |
| 2022 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis. Front Endocrinol (Lausanne). 2023; 14:1087053.
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Insulin-like growth factor 1 and the hormonal mediation of sibling rivalry. Gen Comp Endocrinol. 2023 Jan 01; 330:114163.
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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection. Cell Death Dis. 2022 Jul 15; 13(7):613.
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Insulin/IGF-1 signaling and heat stress differentially regulate HSF1 activities in germline development. Cell Rep. 2021 08 31; 36(9):109623.
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17a-Estradiol Modulates IGF1 and Hepatic Gene Expression in a Sex-Specific Manner. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):778-785.
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Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in vitro. Theriogenology. 2021 Jul 01; 168:1-12.
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Preconceptional Lipid-Based Nutrient Supplementation in 2 Low-Resource Countries Results in Distinctly Different IGF-1/mTOR Placental Responses. J Nutr. 2021 03 11; 151(3):556-569.
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The Impact of Insulin-Like Growth Factor Index and Biologically Effective Dose on Outcomes After Stereotactic Radiosurgery for Acromegaly: Cohort Study. Neurosurgery. 2020 09 01; 87(3):538-546.
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Severe growth failure associated with a novel heterozygous nonsense mutation in the GHR transmembrane domain leading to elevated growth hormone binding protein. Clin Endocrinol (Oxf). 2020 04; 92(4):331-337.
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Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function. Mol Neurobiol. 2020 Mar; 57(3):1317-1331.