Insulin-Like Growth Factor II
"Insulin-Like Growth Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
| Descriptor ID |
D007335
|
| MeSH Number(s) |
D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420
|
| Concept/Terms |
Insulin-Like Growth Factor II- Insulin-Like Growth Factor II
- IGF-II
- Insulin Like Growth Factor II
- Insulin-Like Somatomedin Peptide II
- Insulin Like Somatomedin Peptide II
- Multiplication-Stimulating Factor
- Factor, Multiplication-Stimulating
- Multiplication Stimulating Factor
- Somatomedin A
- Somatomedin MSA
- IGF-2
- Multiplication-Stimulating Activity
- Multiplication Stimulating Activity
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor II".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor II".
This graph shows the total number of publications written about "Insulin-Like Growth Factor II" by people in this website by year, and whether "Insulin-Like Growth Factor II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 0 | 3 | 3 |
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor II" by people in Profiles.
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Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants. Physiol Genomics. 2014 Dec 01; 46(23):851-7.
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Abnormalities in the growth hormone axis and risk of nonalcoholic steatohepatitis: active player or innocent bystander? J Pediatr. 2014 Jul; 165(1):12-4.
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Development of a Grp94 inhibitor. J Am Chem Soc. 2012 Jun 13; 134(23):9796-804.
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Insulin-like growth factor (IGF) 2 stimulates steroidogenesis and mitosis of bovine granulosa cells through the IGF1 receptor: role of follicle-stimulating hormone and IGF2 receptor. Biol Reprod. 2007 Jul; 77(1):18-27.
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Endocrine disruption of uterine insulin-like growth factor expression in the pregnant gilt. Reproduction. 2005 Oct; 130(4):545-51.
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Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines. Cancer Epidemiol Biomarkers Prev. 2005 Jul; 14(7):1646-52.
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The IGF system in the neonatal ovine uterus. Reproduction. 2005 Mar; 129(3):337-47.
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Pregnancy-associated plasma protein-A and insulin-like growth factor binding protein mRNAs in granulosa cells of dominant and subordinate follicles of preovulatory cattle. Domest Anim Endocrinol. 2005 Jan; 28(1):46-63.
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Effect of insulin-like growth factors (IGF), FSH, and leptin on IGF-binding-protein mRNA expression in bovine granulosa and theca cells: quantitative detection by real-time PCR. Peptides. 2004 Dec; 25(12):2195-203.
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Insulin-like growth factor-II stimulates steroidogenesis in cultured bovine thecal cells. Mol Cell Endocrinol. 2004 Nov 30; 227(1-2):1-7.