"Mitomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
| Descriptor ID |
D008937
|
| MeSH Number(s) |
D02.806.400.249 D03.383.097.500 D03.633.100.473.412.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitomycins".
Below are MeSH descriptors whose meaning is more specific than "Mitomycins".
This graph shows the total number of publications written about "Mitomycins" by people in this website by year, and whether "Mitomycins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitomycins" by people in Profiles.
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Suppression of P-glycoprotein expression and multidrug resistance by DNA cross-linking agents. Clin Cancer Res. 1997 Aug; 3(8):1339-46.
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Pharmacodynamic evaluation of mitomycin C analog BMS-181174 for potential use in intravesical bladder cancer therapy. Pharm Res. 1997 Feb; 14(2):241-5.
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Histocultures of patient head and neck tumors for pharmacodynamics studies. Pharm Res. 1993 Oct; 10(10):1493-9.
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Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. Ophthalmology. 1992 Mar; 99(3):438-44.
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Bladder wall penetration of intravesical mitomycin C in dogs. Cancer Res. 1991 Aug 15; 51(16):4347-54.
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Pharmacodynamics of mitomycin C in cultured human bladder tumors. Cancer Res. 1991 Aug 01; 51(15):3849-56.
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A method to study drug concentration-depth profiles in tissues: mitomycin C in dog bladder wall. Pharm Res. 1991 Feb; 8(2):168-73.
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Cultured human bladder tumors for pharmacodynamic studies. J Urol. 1991 Jan; 145(1):203-7.
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High-performance liquid chromatographic determination of mitomycin C in rat and human plasma and urine. J Chromatogr. 1989 Oct 27; 495:330-7.
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Sister chromatid exchange and chromosome fragility in the nevoid basal cell carcinoma syndrome. Cancer Genet Cytogenet. 1989 Oct 15; 42(2):273-9.