"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
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| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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Comparison of a salivary/sputum pepsin assay with 24-hour esophageal pH monitoring for detection of gastric reflux into the proximal esophagus, oropharynx, and lung. Dig Dis Sci. 2003 Sep; 48(9):1813-7.
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Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2. J Biol Chem. 1991 Jul 15; 266(20):13064-9.
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Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2. J Biol Chem. 1991 Jul 15; 266(20):13070-5.