"2-Acetylaminofluorene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Descriptor ID |
D015073
|
| MeSH Number(s) |
D02.065.064.150 D02.241.081.018.110.080 D02.455.426.559.847.389.050 D04.615.389.050
|
| Concept/Terms |
2-Acetylaminofluorene- 2-Acetylaminofluorene
- 2 Acetylaminofluorene
- 2-Acetamidofluorene
- 2 Acetamidofluorene
- 2-Fluorenylacetamide
- 2 Fluorenylacetamide
- N-2-Fluorenylacetamide
- N 2 Fluorenylacetamide
- N-Acetyl-2-Aminofluorene
- N Acetyl 2 Aminofluorene
- AAF, Aminofluorene
- Aminofluorene AAF
- 2-AAF
- Fluoren-2-ylacetamide
- Fluoren 2 ylacetamide
|
Below are MeSH descriptors whose meaning is more general than "2-Acetylaminofluorene".
Below are MeSH descriptors whose meaning is more specific than "2-Acetylaminofluorene".
This graph shows the total number of publications written about "2-Acetylaminofluorene" by people in this website by year, and whether "2-Acetylaminofluorene" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
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Below are the most recent publications written about "2-Acetylaminofluorene" by people in Profiles.
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Evidence of two separate mechanisms for the decrease in aryl sulfotransferase activity in rat liver during early stages of 2-acetylaminofluorene-induced hepatocarcinogenesis. Mol Carcinog. 1994 Jan; 9(1):2-9.
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Changes in levels of ADP-ribose polymers in rat liver during 2-acetylaminofluorene-induced hepatocarcinogenesis. Carcinogenesis. 1993 Jul; 14(7):1435-40.
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Application of quantitative stereology to the evaluation of phenotypically heterogeneous enzyme-altered foci in the rat liver. J Natl Cancer Inst. 1986 Apr; 76(4):751-67.
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Growth of carcinogen-altered rat hepatocytes in the liver of syngeneic recipients promoted with phenobarbital. Cancer Res. 1985 Dec; 45(12 Pt 1):6063-70.