"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
| Descriptor ID |
D015638
|
| MeSH Number(s) |
D03.633.100.473.231.450 D23.946.587.370.450
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
Below are MeSH descriptors whose meaning is more specific than "Cytochalasin D".
This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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Predictable fibroblast tension generation by measuring compaction of anchored collagen matrices using microscopy and optical coherence tomography. Cell Adh Migr. 2019 12; 13(1):303-314.
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Tetraspanin-enriched microdomains regulate digitation junctions. Cell Mol Life Sci. 2018 09; 75(18):3423-3439.
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The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets. Am J Physiol Cell Physiol. 2007 May; 292(5):C1690-700.
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Activity-dependent liberation of synaptic neuropeptide vesicles. Nat Neurosci. 2005 Feb; 8(2):173-8.
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Listeria monocytogenes infection and activation of human brain microvascular endothelial cells. J Infect Dis. 1998 Dec; 178(6):1658-66.
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Listeria monocytogenes virulence factors that stimulate endothelial cells. Infect Immun. 1998 Jan; 66(1):232-8.
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Different mechanisms regulate the monoclonal antibody-induced modulation of CD2, CD3, and CD5 in human lymphocytes. Cell Immunol. 1993 Apr 01; 147(2):247-55.
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PDGF and neomycin induce similar changes in the actin cytoskeleton in human fibroblasts. Cell Motil Cytoskeleton. 1993; 24(2):139-49.