"CD4 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
| Descriptor ID |
D015704
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.810.500 D12.776.543.750.830.700.025 D23.050.301.264.894.100 D23.101.100.894.100
|
| Concept/Terms |
CD4 Antigens- CD4 Antigens
- Antigens, CD4
- CD4 Molecule
- T4 Antigens, T-Cell
- Antigens, T-Cell T4
- T-Cell T4 Antigens
- T4 Antigens, T Cell
- Receptors, CD4
- Surface CD4 Receptor
- CD4 Receptor, Surface
- Receptors, Surface CD4
- CD4 Receptors, Surface
- Surface CD4 Receptors
- CD4 Antigen
- Antigen, CD4
- CD4 Receptors
|
Below are MeSH descriptors whose meaning is more general than "CD4 Antigens".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-16 [D12.776.543.750.705.852.420.810]
- CD4 Antigens [D12.776.543.750.705.852.420.810.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- CD4 Antigens [D12.776.543.750.830.700.025]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD4 Antigens [D23.050.301.264.894.100]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD4 Antigens [D23.101.100.894.100]
Below are MeSH descriptors whose meaning is more specific than "CD4 Antigens".
This graph shows the total number of publications written about "CD4 Antigens" by people in this website by year, and whether "CD4 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CD4 Antigens" by people in Profiles.
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TScan-II: A genome-scale platform for the de novo identification of CD4+ T?cell epitopes. Cell. 2023 Dec 07; 186(25):5569-5586.e21.
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CD4+CD28+KIR+CD11ahi T cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients. J Autoimmun. 2018 01; 86:19-28.
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Study of CD4+CD8+ double positive T-lymphocyte phenotype and function in Indian patients infected with HIV-1. J Med Virol. 2012 Jun; 84(6):845-56.
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Cutaneous CD4+ CD56+ hematologic malignancies. J Am Acad Dermatol. 2010 Aug; 63(2):292-308.
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Differential IL-7 responses in developing human thymocytes. Hum Immunol. 2010 Apr; 71(4):329-33.
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Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases. Pediatr Infect Dis J. 2008 Oct; 27(10 Suppl):S92-6.
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Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals. J Immunol. 2007 Nov 15; 179(10):6845-55.
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Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 2007 May; 56(5):1497-506.
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A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science. 2003 Sep 19; 301(5640):1725-8.
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Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells. Infect Immun. 1998 Oct; 66(10):4696-9.