"Dideoxynucleosides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
| Descriptor ID |
D015224
|
| MeSH Number(s) |
D13.570.230.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dideoxynucleosides".
Below are MeSH descriptors whose meaning is more specific than "Dideoxynucleosides".
This graph shows the total number of publications written about "Dideoxynucleosides" by people in this website by year, and whether "Dideoxynucleosides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Dideoxynucleosides" by people in Profiles.
-
Imaging of subclinical haemopoiesis after stem-cell transplantation in patients with haematological malignancies: a prospective pilot study. Lancet Haematol. 2018 Jan; 5(1):e44-e52.
-
Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk in the Mma Bana Study, Botswana. Antivir Ther. 2013; 18(4):585-90.
-
Abacavir induces loading of novel self-peptides into HLA-B*57: 01: an autoimmune model for HLA-associated drug hypersensitivity. AIDS. 2012 Jul 17; 26(11):F21-9.
-
Macrocytosis is a predictor of resting lactate concentrations in persons on dideoxynucleoside therapy for HIV infection. Int J Infect Dis. 2012 Apr; 16(4):e225-7.
-
[18F]fluorothymidine PET imaging in the diagnosis of leptomeningeal involvement with diffuse large B-cell lymphoma. Cancer Imaging. 2011 Sep 24; 11:140-3.
-
F-18-fluorothymidine-PET evaluation of bone marrow transplant in a rat model. Nucl Med Commun. 2010 Feb; 31(2):152-8.
-
Management protocol for abacavir-related hypersensitivity reaction. Ann Pharmacother. 2000 Feb; 34(2):247-9.