"Superoxides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
| Descriptor ID |
D013481
|
| MeSH Number(s) |
D01.248.497.158.685.750.850 D01.339.431.374.850 D01.650.550.750.800 D02.389.338.732
|
| Concept/Terms |
Superoxides- Superoxides
- Superoxide Anion
- Superoxide Radical
- Superoxide
|
Below are MeSH descriptors whose meaning is more general than "Superoxides".
Below are MeSH descriptors whose meaning is more specific than "Superoxides".
This graph shows the total number of publications written about "Superoxides" by people in this website by year, and whether "Superoxides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 1 | 3 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 5 | 6 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 2 | 4 |
| 2006 | 1 | 2 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 4 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 3 | 3 |
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Below are the most recent publications written about "Superoxides" by people in Profiles.
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Selective Ablation of Sod2 in Astrocytes Induces Sex-Specific Effects on Cognitive Function, d-Serine Availability, and Astrogliosis. J Neurosci. 2022 08 03; 42(31):5992-6006.
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Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia-Reperfusion. Int J Mol Sci. 2022 Mar 21; 23(6).
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In Vivo Cardiac-specific Expression of Adenylyl Cyclase 4 Gene Protects against Klotho Deficiency-induced Heart Failure. Transl Res. 2022 06; 244:101-113.
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Mitochondria in Sepsis-Induced AKI. J Am Soc Nephrol. 2019 07; 30(7):1151-1161.
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Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes. Redox Biol. 2019 Oct; 27:101141.
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A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer. J Pharmacol Exp Ther. 2015 May; 353(2):392-404.
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Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. Biochem J. 2014 Sep 01; 462(2):359-71.
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Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart. Am J Physiol Heart Circ Physiol. 2014 Mar 01; 306(5):H709-17.
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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) activity by small molecule GMX1778 regulates reactive oxygen species (ROS)-mediated cytotoxicity in a p53- and nicotinic acid phosphoribosyltransferase1 (NAPRT1)-dependent manner. J Biol Chem. 2012 Jun 22; 287(26):22408-17.
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Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production. Age (Dordr). 2011 Sep; 33(3):261-74.