"Quinolinic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
| Descriptor ID |
D017378
|
| MeSH Number(s) |
D03.383.725.822.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Quinolinic Acid".
Below are MeSH descriptors whose meaning is more specific than "Quinolinic Acid".
This graph shows the total number of publications written about "Quinolinic Acid" by people in this website by year, and whether "Quinolinic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Quinolinic Acid" by people in Profiles.
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Acute administration of ibuprofen increases serum concentration of the neuroprotective kynurenine pathway metabolite, kynurenic acid: a pilot randomized, placebo-controlled, crossover study. Psychopharmacology (Berl). 2022 Dec; 239(12):3919-3927.
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C-Reactive protein and the kynurenic acid to quinolinic acid ratio are independently associated with white matter integrity in major depressive disorder. Brain Behav Immun. 2022 10; 105:180-189.
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Sleep disturbance and kynurenine metabolism in depression. J Psychosom Res. 2017 08; 99:1-7.
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Serum kynurenic acid is reduced in affective psychosis. Transl Psychiatry. 2017 05 02; 7(5):e1115.
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Abnormalities in Functional Connectivity in Collegiate Football Athletes with and without a Concussion History: Implications and Role of Neuroactive Kynurenine Pathway Metabolites. J Neurotrauma. 2017 02 15; 34(4):824-837.
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Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression. Brain Behav Immun. 2016 Aug; 56:335-42.
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Smaller Dentate Gyrus and CA2 and CA3 Volumes Are Associated with Kynurenine Metabolites in Collegiate Football Athletes. J Neurotrauma. 2016 07 15; 33(14):1349-57.
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Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain Behav Immun. 2016 Mar; 53:39-48.
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Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder. Psychoneuroendocrinology. 2015 Dec; 62:54-8.
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Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain Behav Immun. 2015 May; 46:55-9.