Insulin-Like Growth Factor Binding Protein 4
"Insulin-Like Growth Factor Binding Protein 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
| Descriptor ID |
D018974
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| MeSH Number(s) |
D12.776.157.420.280
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 4".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 4".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 4" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 4" by people in Profiles.
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Effect of growth hormone administration to mature miniature Brahman cattle treated with or without insulin on circulating concentrations of insulin-like growth factor-I and other metabolic hormones and metabolites. Domest Anim Endocrinol. 2011 Jul; 41(1):1-13.
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The IGF system in the neonatal ovine uterus. Reproduction. 2005 Mar; 129(3):337-47.
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Pregnancy-associated plasma protein-A and insulin-like growth factor binding protein mRNAs in granulosa cells of dominant and subordinate follicles of preovulatory cattle. Domest Anim Endocrinol. 2005 Jan; 28(1):46-63.
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Effect of insulin-like growth factors (IGF), FSH, and leptin on IGF-binding-protein mRNA expression in bovine granulosa and theca cells: quantitative detection by real-time PCR. Peptides. 2004 Dec; 25(12):2195-203.
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Insulin-like growth factor-I and its binding proteins in colostrum compared to measures in serum of Holstein neonates. J Dairy Sci. 2003 Jun; 86(6):2022-9.
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Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. J Bone Miner Res. 2003 May; 18(5):836-43.
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Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy. J Biol Chem. 2002 Jun 14; 277(24):21285-90.
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IGF-binding protein-4 expression and IGF-binding protein-4 protease activity are regulated coordinately in smooth muscle during postnatal development and after vascular injury. Endocrinology. 2001 Oct; 142(10):4420-7.
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Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5. J Cell Physiol. 1998 Oct; 177(1):47-57.
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Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia. Endocrinology. 1998 May; 139(5):2605-14.