"Sp1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
| Descriptor ID |
D016329
|
| MeSH Number(s) |
D12.776.260.522.750.249 D12.776.930.375.750.249
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sp1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Sp1 Transcription Factor".
This graph shows the total number of publications written about "Sp1 Transcription Factor" by people in this website by year, and whether "Sp1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Sp1 Transcription Factor" by people in Profiles.
-
Anti-inflammatory mediators ST2 and SIGIRR are induced by diphenyldifluoroketone EF24 in lipopolysaccharide-stimulated dendritic cells. Immunobiology. 2020 03; 225(2):151886.
-
Role of cystathionine beta synthase in lipid metabolism in ovarian cancer. Oncotarget. 2015 Nov 10; 6(35):37367-84.
-
SK3 channel expression during pregnancy is regulated through estrogen and Sp factor-mediated transcriptional control of the KCNN3 gene. Am J Physiol Endocrinol Metab. 2010 Oct; 299(4):E640-6.
-
Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite. J Inorg Biochem. 2009 Mar; 103(3):419-26.
-
Endogenous S-nitrosoglutathione modifies 5-lipoxygenase expression in airway epithelial cells. Am J Respir Cell Mol Biol. 2006 Apr; 34(4):387-93.
-
Cloning of the murine ER71 gene (Etsrp71) and initial characterization of its promoter. Genomics. 2005 Apr; 85(4):493-502.
-
Cys redox reactions and metal binding of a Cys2His2 zinc finger. Arch Biochem Biophys. 2005 Feb 01; 434(1):139-49.
-
Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma. Clin Cancer Res. 2004 Feb 15; 10(4):1344-53.
-
Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Mol Cell Biol. 2003 Jan; 23(2):526-33.
-
Inhibition of zinc finger protein-DNA interactions by sodium selenite. Biochem Pharmacol. 2002 Dec 15; 64(12):1757-65.