"Aflatoxin B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.
| Descriptor ID |
D016604
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| MeSH Number(s) |
D03.383.663.283.119.075 D03.633.100.150.119.075 D23.946.587.142.075
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aflatoxin B1".
Below are MeSH descriptors whose meaning is more specific than "Aflatoxin B1".
This graph shows the total number of publications written about "Aflatoxin B1" by people in this website by year, and whether "Aflatoxin B1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aflatoxin B1" by people in Profiles.
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The inflammation response and risk associated with aflatoxin B1 contamination was minimized by insect peptide CopA3 treatment and act towards the beneficial health outcomes. Environ Pollut. 2021 Jan 01; 268(Pt B):115713.
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Aflatoxin B1 induces reactive oxygen species-dependent caspase-mediated apoptosis in normal human cells, inhibits Allium cepa root cell division, and triggers inflammatory response in zebrafish larvae. Sci Total Environ. 2020 Oct 01; 737:139704.
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Natural-Product-Inspired Compounds as Countermeasures against the Liver Carcinogen Aflatoxin B1. J Nat Prod. 2019 06 28; 82(6):1694-1703.
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In vivo detection of aflatoxin-induced lipid free radicals in rat bile. Biochim Biophys Acta. 2002 Oct 10; 1573(1):55-62.